112398-08-0

112398-08-0 structure

Name: Danofloxacine
Chemical Name: Danofloxacin
CAS Number: 112398-08-0
Molecular Formula: C₁₉H₂₀FN₃O₃
Molecular Weight: 357.379
Catalog: API Synthetic anti-infective drugs Quinolone
Create Date: 2018-07-23 16:55:08
Modify Date: 2026-07-01 14:00:34
Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase. Danofloxacinh has the potential for respiratory diseases in cattle, swine, and chickens treatment[1][2].

Name	Danofloxacin
Synonyms	Danofloxacin, Vetranal 1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid DANOFLOXACIN DANOFLOXACIN //BP Danofloxacin 100 μg/mL in Acetonitrile danofloxacin Danofloxacino Dafloxacin 1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Danofloxacin free base 3-Quinolinecboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-Methyl-2,5-diazabicyclo[2.2.1]ht-2-yl]-4-oxo (1S)-1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl)-4-oxo-3-quinolinecarboxylic acid ADVOCIN(R) DANOFLOXACIN BASE Danofloxacin solution,1000ppm 1-cyclopropyl-6-fluoro-7-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]htan-2-yl)-4-oxo-1,4-dihydroquinoline-3-cboxylic acid DanofloxacinQ: What is Danofloxacin Q: What is the CAS Number of Danofloxacin Q: What is the storage condition of Danofloxacin Chlorotoluron Impurity 12 Hydrochloride (Chlordimeform Hydrochloride) 1-Cyclopropyl-6-Fluoro-7-[(1S,4S)-3-Methyl-3,6-Diazabicyclo[2.2.1]Htan-6-Yl]-4-Oxo-Quinoline-3-Cboxylic Acid Inhibitor,Antibiotic,DNA-gyrase,respiratory,mycoplasma,inhibit,Fluoroquinolone,Danofloxacin,am-positive,DNA/RNA Synthesis,orally,chlamydia,bacteria,am-negative,Bacterial,antimicrobial Danofloxacin,Advocin Danofloxacin Solution, 100ppm Danofloxacininmethanol advocin

Description	Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase. Danofloxacinh has the potential for respiratory diseases in cattle, swine, and chickens treatment[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Erjie Tian, et al. Population Pharmacokinetics for Danofloxacin in the Intestinal Contents of Healthy and Infected Chickens. J Vet Pharmacol Ther. 2019 Sep;42(5):556-563. [2]. Xia Xiao, et al. Comparative Pharmacokinetics of Danofloxacin in Healthy and Pasteurella Multocida Infected Ducks. J Vet Pharmacol Ther. 2018 Dec;41(6):912-918.

Density	1.5±0.1 g/cm3
Boiling Point	569.3±50.0 °C at 760 mmHg
Melting Point	268-272ºC
Molecular Formula	C₁₉H₂₀FN₃O₃
Molecular Weight	357.379
Flash Point	298.1±30.1 °C
Exact Mass	357.148865
PSA	65.78000
LogP	1.20
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.679
Water Solubility	Soluble in water, acetic acid and DMSO

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn,Xi
Risk Phrases	20/21/22-36/37/38
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport

93107-30-3

52321-26-3

~78%

112398-08-0

Precursor 1
93107-30-3
DownStream 0