Danofloxacine
Danofloxacine structure
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Common Name | Danofloxacine | ||
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| CAS Number | 112398-08-0 | Molecular Weight | 357.379 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 569.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C19H20FN3O3 | Melting Point | 268-272ºC | |
| MSDS | Chinese USA | Flash Point | 298.1±30.1 °C | |
Use of DanofloxacineDanofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase. Danofloxacinh has the potential for respiratory diseases in cattle, swine, and chickens treatment[1][2]. |
| Name | Danofloxacin |
|---|---|
| Synonym | More Synonyms |
| Description | Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase. Danofloxacinh has the potential for respiratory diseases in cattle, swine, and chickens treatment[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 569.3±50.0 °C at 760 mmHg |
| Melting Point | 268-272ºC |
| Molecular Formula | C19H20FN3O3 |
| Molecular Weight | 357.379 |
| Flash Point | 298.1±30.1 °C |
| Exact Mass | 357.148865 |
| PSA | 65.78000 |
| LogP | 1.20 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.679 |
| Water Solubility | Soluble in water, acetic acid and DMSO |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn,Xi |
| Risk Phrases | 20/21/22-36/37/38 |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
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~78%
Danofloxacine CAS#:112398-08-0 |
| Literature: McGuirk; Jefson; Mann; Elliott; Chang; Cisek; Cornell; Gootz; Haskell; Hindahl; LaFleur; Rosenfeld; Shryock; Silvia; Weber Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 611 - 620 |
![2-Methyl-2,5-diaza-bicyclo[2.2.1]heptanedihydrochloride structure](https://image.chemsrc.com/caspic/086/52321-26-3.png)
| Precursor 1 | |
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| DownStream 0 | |
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Multiresidue determination of fluoroquinolones in poultry muscle and kidney according to the regulation 2002/657/EC. A systematic comparison of two different approaches: Liquid chromatography coupled to high-resolution mass spectrometry or tandem mass spectrometry.
J. Chromatogr. A. 1379 , 83-91, (2015) This work involved the optimization and validation of two methods according to the Commission Decision 2002/657/EC directives for determining fluoroquinolones residues in samples of poultry muscle and... |
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Simultaneous determination of 38 veterinary antibiotic residues in raw milk by UPLC-MS/MS.
Food Chem. 181 , 119-26, (2015) A selective and rapid method has been developed to determine, simultaneously, 38 veterinary antibiotic residues in raw milk by ultra-high-performance liquid chromatography-tandem mass spectrometry (UP... |
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Decay mechanisms of protonated 4-quinolone antibiotics after electrospray ionization and ion activation.
J. Am. Soc. Mass Spectrom. 25(11) , 1974-86, (2014) This study presents a detailed experimental investigation of charge isomers of protonated 4-quinolone antibiotics molecules formed during electrospray ionization (ESI) with proposed dissociation mecha... |
| 1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid |
| danofloxacin |
| 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo- |
| 1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
| (1S)-1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl)-4-oxo-3-quinolinecarboxylic acid |