139755-85-4
139755-85-4 structure
- Name: Hydroxyhomo Sildenafil
- Chemical Name: 5-[2-ethoxy-5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
- CAS Number: 139755-85-4
- Molecular Formula: C23H32N6O5S
- Molecular Weight: 504.60200
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
- Create Date: 2018-10-17 14:49:47
- Modify Date: 2025-08-29 20:58:55
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Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED), with less oral bioavailability than Lodenafil carbonate[1].
| Name | 5-[2-ethoxy-5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one |
|---|---|
| Synonyms |
hydroxyhomosildenafil
Hydroxyhomo Sildenafil |
| Description | Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED), with less oral bioavailability than Lodenafil carbonate[1]. |
|---|---|
| Related Catalog | |
| Target |
PDE5 |
| References |
| Density | 1.42g/cm3 |
|---|---|
| Boiling Point | 730.6ºC at 760 mmHg |
| Melting Point | 183-185 °C |
| Molecular Formula | C23H32N6O5S |
| Molecular Weight | 504.60200 |
| Flash Point | 395.7ºC |
| Exact Mass | 504.21500 |
| PSA | 142.03000 |
| LogP | 1.93000 |
| Vapour Pressure | 2.08E-22mmHg at 25°C |
| Index of Refraction | 1.667 |
| Hazard Codes | Xi |
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139755-85-4 |
| Literature: Journal of Medicinal Chemistry, , vol. 51, # 9 p. 2807 - 2815 |
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139755-85-4 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 15 p. 1819 - 1824 |
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139755-85-4 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 15 p. 1819 - 1824 |
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139755-85-4 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 15 p. 1819 - 1824 |
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139755-85-4 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 15 p. 1819 - 1824 |
| Precursor 6 | |
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| DownStream 0 | |