Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4,6-Dioxoheptanoic acid
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Purity: 98.0%
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DC Chemicals Limited
China
Product Name: NSC 174804
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Purity: 98.0%
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: NSC 174804
Price: ￥Inquiry/1g
Purity: 98.9%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4,6-Dioxoheptanoic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

51568-18-4

51568-18-4 structure

51568-18-4 structure

Name: 4,6-Dioxoheptanoic acid
Chemical Name: 4,6-dioxoheptanoic acid
CAS Number: 51568-18-4
Molecular Formula: C₇H₁₀O₄
Molecular Weight: 158.15200
Catalog: analytical chemistry food safety Fatty acid, fatty acid methyl ester
Create Date: 2018-03-22 08:00:00
Modify Date: 2024-01-05 17:58:56
4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.

Name	4,6-dioxoheptanoic acid
Synonyms	4,6-Dioxoheptanoic acid Succinylacetone 4,6-DIOXOHEPTANOIC ACID

Description	4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Cardiovascular Disease
Target	Human Endogenous Metabolite
In Vitro	4,6-Dioxoheptanoic acid (Succinylacetone, SA) is examined with regard to its ability to a) inhibit the second enzyme of the heme pathway, δ-aminolevulinic acid (ALA) dehydratase, b) lower the heme concentration, and c) inhibit cell growth of murine erythroleukemia (MEL) cells in culture[1].
References	[1]. Ebert PS, et al. Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme contentand delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem Biophys Res Commun. 1979 Jun 27;88(4):1382-90.

Density	1.189 g/cm3
Boiling Point	318.7ºC at 760 mmHg
Melting Point	66-67ºC
Molecular Formula	C₇H₁₀O₄
Molecular Weight	158.15200
Flash Point	160.8ºC
Exact Mass	158.05800
PSA	71.44000
LogP	0.39940
Index of Refraction	1.455
Storage condition	2-8°C

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2918300090

79-11-8 structure

79-11-8

123-54-6 structure

123-54-6

~%

51568-18-4 structure

51568-18-4

Literature: Pendarvis,R.O.; Hampton,K.G. Journal of Organic Chemistry, 1974 , vol. 39, p. 2289 - 2291

Precursor 2
79-11-8 123-54-6
DownStream 0

HS Code	2918300090
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%