643-12-9

643-12-9 structure

Name: D-(+)-CHIRO-INOSITOL
Chemical Name: d-(+)-chiro-inositol
CAS Number: 643-12-9
Molecular Formula: C₆H₁₂O₆
Molecular Weight: 180.156
Catalog: Biochemical Carbohydrate Monosaccharide
Create Date: 2018-05-17 08:00:00
Modify Date: 2024-01-06 10:05:48
D-chiro-Inositol is an epimer of myo-inositol found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. D-chiro-Inositol is used clinically for the treatment of polycystic ovary syndrome (PCOS) and diabetes mellitus, which can reduce hyperglycemia and ameliorate insulin resistance[1][2][3].

Name	d-(+)-chiro-inositol
Synonyms	cyclohexanehexol D-Inositol (1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-Cyclohexanehexol 1,2,3,4,5,6-Cyclohexanehexol, (1α,2α,3β,4α,5β,6β)- (1R,2R,3S,4S,5S,6S)-Cyclohexane-1,2,3,4,5,6-hexol (1R,2R,3S,4S,5S,6S)-Cyclohexan-1,2,3,4,5,6-hexol 1,2,4/3,5,6-hexahydroxycyclohexane 1D-chiro-Inositol (+)-1,2,4/3,5,6-Inositol cis-inositol EINECS 211-394-0 D-Chiro-inositol(DCI) D-CHIRO-INOSITOL(DISD) MFCD00272608 D-(+)-Inositol D-chiro-inositol

Description	D-chiro-Inositol is an epimer of myo-inositol found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. D-chiro-Inositol is used clinically for the treatment of polycystic ovary syndrome (PCOS) and diabetes mellitus, which can reduce hyperglycemia and ameliorate insulin resistance[1][2][3].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Ostlund RE Jr, et al. A stereospecific myo-inositol/D-chiro-inositol transporter in HepG2 liver cells. Identification with D-chiro-[3-3H]inositol. J Biol Chem. 1996 Apr 26;271(17):10073-8. [2]. Zhao SS, et al. D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acidsecretion and attenuating oxidative stress. Acta Pharmacol Sin. 2018 Feb;39(2):213-221. [3]. Cheng F, et al. chiro-Inositol Ameliorates High Fat Diet-Induced Hepatic Steatosis and Insulin Resistance viaPKCε-PI3K/AKT Pathway. J Agric Food Chem. 2019 May 29;67(21):5957-5967.

HS Code	29061390