DC Chemicals Limited
China
Product Name: VUF-5574
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

280570-45-8

280570-45-8 structure

280570-45-8 structure

Name: VUF 5574
Chemical Name: 1-(2-methoxyphenyl)-3-(2-pyridin-3-ylquinazolin-4-yl)urea
CAS Number: 280570-45-8
Molecular Formula: C₂₁H₁₇N₅O₂
Molecular Weight: 371.39200
Create Date: 2016-03-24 19:08:35
Modify Date: 2024-01-10 18:32:11
VUF-5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor[1].

Name	1-(2-methoxyphenyl)-3-(2-pyridin-3-ylquinazolin-4-yl)urea
Synonyms	VUF 5574 Lopac-V-5888

Description	VUF-5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor[1].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	Recombinant Human Adenosine A3 receptor (A3R):4.03 nM (Ki)
References	[1]. van Muijlwijk-Koezen JE, et al. Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem. 2000 Jun 1;43(11):2227-38.

Density	1.36g/cm3
Boiling Point	444.8ºC at 760 mmHg
Molecular Formula	C₂₁H₁₇N₅O₂
Molecular Weight	371.39200
Flash Point	222.8ºC
Exact Mass	371.13800
PSA	89.03000
LogP	4.49040
Vapour Pressure	4.14E-08mmHg at 25°C
Index of Refraction	1.725

Safety Phrases	22-24/25