VUF 5574

Modify Date: 2024-01-10 18:32:11

VUF 5574 Structure
VUF 5574 structure
Common Name VUF 5574
CAS Number 280570-45-8 Molecular Weight 371.39200
Density 1.36g/cm3 Boiling Point 444.8ºC at 760 mmHg
Molecular Formula C21H17N5O2 Melting Point N/A
MSDS Chinese USA Flash Point 222.8ºC

 Use of VUF 5574


VUF-5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor[1].

 Names

Name 1-(2-methoxyphenyl)-3-(2-pyridin-3-ylquinazolin-4-yl)urea
Synonym More Synonyms

 VUF 5574 Biological Activity

Description VUF-5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor[1].
Related Catalog
Target

Recombinant Human Adenosine A3 receptor (A3R):4.03 nM (Ki)

References

[1]. van Muijlwijk-Koezen JE, et al. Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem. 2000 Jun 1;43(11):2227-38.

 Chemical & Physical Properties

Density 1.36g/cm3
Boiling Point 444.8ºC at 760 mmHg
Molecular Formula C21H17N5O2
Molecular Weight 371.39200
Flash Point 222.8ºC
Exact Mass 371.13800
PSA 89.03000
LogP 4.49040
Vapour Pressure 4.14E-08mmHg at 25°C
Index of Refraction 1.725

 Safety Information

Safety Phrases 22-24/25

 Synonyms

VUF 5574
Lopac-V-5888