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853-34-9

853-34-9 structure
853-34-9 structure
  • Name: Kebuzone
  • Chemical Name: kebuzone
  • CAS Number: 853-34-9
  • Molecular Formula: C19H18N2O3
  • Molecular Weight: 322.358
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-07-07 22:38:29
  • Modify Date: 2024-01-02 18:00:54
  • Kebuzone is a non-steroidal anti-inflammatory substance that may be studied in inflammatory diseases such as thrombophlebitis and rheumatoid arthritis[1].
Name kebuzone
Synonyms Chebutan
4-(3-Oxobutyl)-1,2-diphenylpyrazolidine-3,5-dione
Recheton
Kebuzone
1,2-Diphenyl-4-(g-ketobutyl)-3,5-pyrazolidinedione
Cetophenylbutazone
ketophenylbutazone
Ketophenylbutazon
Ketazon
Chetazolidin
Copirene
Ketason
3,5-Pyrazolidinedione, 4-(3-oxobutyl)-1,2-diphenyl-
4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione
Chepirol
Ketazone
Description Kebuzone is a non-steroidal anti-inflammatory substance that may be studied in inflammatory diseases such as thrombophlebitis and rheumatoid arthritis[1].
Related Catalog
Density 1.2±0.1 g/cm3
Boiling Point 462.8±37.0 °C at 760 mmHg
Molecular Formula C19H18N2O3
Molecular Weight 322.358
Flash Point 199.5±18.9 °C
Exact Mass 322.131744
PSA 57.69000
LogP 1.25
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.599

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ8540000
CHEMICAL NAME :
3,5-Pyrazolidinedione, 1,2-diphenyl-4-(3-oxobutyl)-
CAS REGISTRY NUMBER :
853-34-9
BEILSTEIN REFERENCE NO. :
0308507
LAST UPDATED :
199612
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C19-H18-N2-O3
MOLECULAR WEIGHT :
322.39
WISWESSER LINE NOTATION :
T5VNNV EHJ BR& CR& E2V1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
720 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,229,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
683 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,229,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
315 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,229,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 22,66,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
662 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
620 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
580 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 16,1339,1966
HS Code 2933990090
122-66-7 structure

122-66-7

~%

853-34-9 structure

853-34-9

Literature: Cesko-Slovenska Farmacie, , vol. 7, p. 303 Chem.Abstr., , p. 1313
116604-64-9 structure

116604-64-9

~%

853-34-9 structure

853-34-9

Literature: Helvetica Chimica Acta, , vol. 40, p. 402,406
7796-23-8 structure

7796-23-8

~%

853-34-9 structure

853-34-9

Literature: Helvetica Chimica Acta, , vol. 40, p. 402,406
10561-01-0 structure

10561-01-0

~%

853-34-9 structure

853-34-9

Literature: Cesko-Slovenska Farmacie, , vol. 7, p. 303 Chem.Abstr., , p. 1313
10553-86-3 structure

10553-86-3

~%

853-34-9 structure

853-34-9

Literature: Cesko-Slovenska Farmacie, , vol. 7, p. 303 Chem.Abstr., , p. 1313
2652-77-9 structure

2652-77-9

~%

853-34-9 structure

853-34-9

Literature: Cesko-Slovenska Farmacie, , vol. 7, p. 303 Chem.Abstr., , p. 1313
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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title: CAS No. 853-34-9 | Chemsrc address: https://m.chemsrc.com/en/baike/754417.html

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