Kebuzone

Modify Date: 2024-01-02 18:00:54

Kebuzone structure	Common Name	Kebuzone
	CAS Number	853-34-9	Molecular Weight	322.358
	Density	1.2±0.1 g/cm3	Boiling Point	462.8±37.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₁₈N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	199.5±18.9 °C

Use of Kebuzone

Kebuzone is a non-steroidal anti-inflammatory substance that may be studied in inflammatory diseases such as thrombophlebitis and rheumatoid arthritis[1].

Name	kebuzone
Synonym	More Synonyms

Description	Kebuzone is a non-steroidal anti-inflammatory substance that may be studied in inflammatory diseases such as thrombophlebitis and rheumatoid arthritis[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology

Density	1.2±0.1 g/cm3
Boiling Point	462.8±37.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₈N₂O₃
Molecular Weight	322.358
Flash Point	199.5±18.9 °C
Exact Mass	322.131744
PSA	57.69000
LogP	1.25
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.599

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ8540000

CHEMICAL NAME :: 3,5-Pyrazolidinedione, 1,2-diphenyl-4-(3-oxobutyl)-

CAS REGISTRY NUMBER :: 853-34-9

BEILSTEIN REFERENCE NO. :: 0308507

LAST UPDATED :: 199612

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C19-H18-N2-O3

MOLECULAR WEIGHT :: 322.39

WISWESSER LINE NOTATION :: T5VNNV EHJ BR& CR& E2V1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 720 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,229,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 683 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,229,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 315 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,229,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 22,66,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 662 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 620 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 580 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 650 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 16,1339,1966

HS Code	2933990090

1,2-Diphenylhyd...

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Kebuzone

CAS#:853-34-9

Literature: Cesko-Slovenska Farmacie, , vol. 7, p. 303 Chem.Abstr., , p. 1313

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Kebuzone

CAS#:853-34-9

Literature: Helvetica Chimica Acta, , vol. 40, p. 402,406

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Kebuzone

CAS#:853-34-9

Literature: Helvetica Chimica Acta, , vol. 40, p. 402,406

4-[(Z)-3-chloro...

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Kebuzone

CAS#:853-34-9

Literature: Cesko-Slovenska Farmacie, , vol. 7, p. 303 Chem.Abstr., , p. 1313

(3-chloro-but-2...

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CAS#:853-34-9

Literature: Cesko-Slovenska Farmacie, , vol. 7, p. 303 Chem.Abstr., , p. 1313

1,2-Diphenyl-py...

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Kebuzone

CAS#:853-34-9

Literature: Cesko-Slovenska Farmacie, , vol. 7, p. 303 Chem.Abstr., , p. 1313

Precursor 5
CAS#:122-66-7 1,2-Diphenylhyd... CAS#:7796-23-8 [2-(2-Methyl-1,... CAS#:10561-01-0 4-[(Z)-3-chloro... CAS#:10553-86-3 (3-chloro-but-2...
CAS#:2652-77-9 1,2-Diphenyl-py...
DownStream 6
CAS#:93371-32-5 2,5-dioxo-N-phe... CAS#:93371-33-6 5,5-dimethoxy-2... CAS#:93371-31-4 2-methoxy-2-(3-... CAS#:93371-35-8 2-(3,3-dimethox...
CAS#:1227476-15-4 1,2-diphenyldiazene CAS#:93371-34-7 2-hydroxy-2-(3-...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Chebutan

4-(3-Oxobutyl)-1,2-diphenylpyrazolidine-3,5-dione

Recheton

Kebuzone

1,2-Diphenyl-4-(g-ketobutyl)-3,5-pyrazolidinedione

Cetophenylbutazone

ketophenylbutazone

Ketophenylbutazon

Ketazon

Chetazolidin

Copirene

Ketason

3,5-Pyrazolidinedione, 4-(3-oxobutyl)-1,2-diphenyl-

4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione

Chepirol

Ketazone

DC Chemicals Limited
China
Product Name: Kebuzone
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3,5-Pyrazolidinedione,4-(3-oxobutyl)-1,2-diphenyl-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Kebuzone

Use of Kebuzone

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Kebuzone Biological Activity

Chemical & Physical Properties

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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Synthetic Route

Precursor & DownStream

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