| Name | 4-Chloro-3-(trifluoromethyl)phenyl isocyanate |
|---|---|
| Synonyms |
Sorafenib intermediate 3
Isocyanic Acid 4-Chloro-3-(trifluoromethyl)phenyl Ester 1-chloro-4-isocyanato-2-trifluoromethylbenzene 3-TRIFLUOROMETHYL-4-CHLORO-PHENYL ISOCYANATE 4-Cl-3CF3-phenyl isocyanate 4-Chloro-3-(trifluoromethyl)phenyl isocyanate MFCD00013874 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene 4-Chloro-3-(trifluoromethyl)phenylisocyanate Benzene, 1-chloro-4-isocyanato-2-(trifluoromethyl)- |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 201.7±0.0 °C at 760 mmHg |
| Melting Point | 40-42 °C(lit.) |
| Molecular Formula | C8H3ClF3NO |
| Molecular Weight | 221.564 |
| Flash Point | 99.4±0.0 °C |
| Exact Mass | 220.985519 |
| PSA | 29.43000 |
| LogP | 4.93 |
| Vapour Pressure | 0.3±0.3 mmHg at 25°C |
| Index of Refraction | 1.487 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H315-H319-H332-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S7-S26-S27-S37/39-S36/37/39-S45-S23 |
| RIDADR | UN 2206 6.1/PG 3 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 2929109000 |
|
~97%
327-78-6 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 11 p. 2960 - 2967 |
|
~%
327-78-6 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 562, p. 75,1114 |
|
~%
327-78-6 |
| Literature: US2012/53192 A1, ; Page/Page column 4 ; |
| Precursor 4 | |
|---|---|
| DownStream 10 | |
| HS Code | 2929109000 |
|---|---|
| Summary | 2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |