Name | 4-Chloro-3-(trifluoromethyl)phenyl isocyanate |
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Synonyms |
Sorafenib intermediate 3
Isocyanic Acid 4-Chloro-3-(trifluoromethyl)phenyl Ester 1-chloro-4-isocyanato-2-trifluoromethylbenzene 3-TRIFLUOROMETHYL-4-CHLORO-PHENYL ISOCYANATE 4-Cl-3CF3-phenyl isocyanate 4-Chloro-3-(trifluoromethyl)phenyl isocyanate MFCD00013874 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene 4-Chloro-3-(trifluoromethyl)phenylisocyanate Benzene, 1-chloro-4-isocyanato-2-(trifluoromethyl)- |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 201.7±0.0 °C at 760 mmHg |
Melting Point | 40-42 °C(lit.) |
Molecular Formula | C8H3ClF3NO |
Molecular Weight | 221.564 |
Flash Point | 99.4±0.0 °C |
Exact Mass | 220.985519 |
PSA | 29.43000 |
LogP | 4.93 |
Vapour Pressure | 0.3±0.3 mmHg at 25°C |
Index of Refraction | 1.487 |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302-H312-H315-H319-H332-H335 |
Precautionary Statements | P261-P280-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn:Harmful; |
Risk Phrases | R20/21/22;R36/37/38 |
Safety Phrases | S7-S26-S27-S37/39-S36/37/39-S45-S23 |
RIDADR | UN 2206 6.1/PG 3 |
WGK Germany | 3 |
Packaging Group | III |
Hazard Class | 6.1 |
HS Code | 2929109000 |
~97% 327-78-6 |
Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 11 p. 2960 - 2967 |
~% 327-78-6 |
Literature: Justus Liebigs Annalen der Chemie, , vol. 562, p. 75,1114 |
~% 327-78-6 |
Literature: US2012/53192 A1, ; Page/Page column 4 ; |
Precursor 4 | |
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DownStream 10 | |
HS Code | 2929109000 |
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Summary | 2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |