4-Chloro-3-(trifluoromethyl)phenylisocyanate

Modify Date: 2024-01-02 14:28:43

4-Chloro-3-(trifluoromethyl)phenylisocyanate structure	Common Name	4-Chloro-3-(trifluoromethyl)phenylisocyanate
	CAS Number	327-78-6	Molecular Weight	221.564
	Density	1.4±0.1 g/cm3	Boiling Point	201.7±0.0 °C at 760 mmHg
	Molecular Formula	C₈H₃ClF₃NO	Melting Point	40-42 °C(lit.)
	MSDS	Chinese USA	Flash Point	99.4±0.0 °C
	Symbol	GHS07	Signal Word	Warning

Name	4-Chloro-3-(trifluoromethyl)phenyl isocyanate
Synonym	More Synonyms

Density	1.4±0.1 g/cm3
Boiling Point	201.7±0.0 °C at 760 mmHg
Melting Point	40-42 °C(lit.)
Molecular Formula	C₈H₃ClF₃NO
Molecular Weight	221.564
Flash Point	99.4±0.0 °C
Exact Mass	220.985519
PSA	29.43000
LogP	4.93
Vapour Pressure	0.3±0.3 mmHg at 25°C
Index of Refraction	1.487

MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H315-H319-H332-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22;R36/37/38
Safety Phrases	S7-S26-S27-S37/39-S36/37/39-S45-S23
RIDADR	UN 2206 6.1/PG 3
WGK Germany	3
Packaging Group	III
Hazard Class	6.1
HS Code	2929109000

Triphosgene

CAS#:32315-10-9

5-Amino-2-chlor...

CAS#:320-51-4

~97%

4-Chloro-3-(tri...

CAS#:327-78-6

Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 11 p. 2960 - 2967

phosgene

CAS#:75-44-5

5-Amino-2-chlor...

CAS#:320-51-4

4-Chloro-3-(tri...

CAS#:327-78-6

Literature: Justus Liebigs Annalen der Chemie, , vol. 562, p. 75,1114

5-Amino-2-chlor...

CAS#:320-51-4

Diphosgene

CAS#:503-38-8

4-Chloro-3-(tri...

CAS#:327-78-6

Literature: US2012/53192 A1, ; Page/Page column 4 ;

Precursor 4
CAS#:32315-10-9 Triphosgene CAS#:320-51-4 5-Amino-2-chlor... CAS#:75-44-5 phosgene CAS#:503-38-8 Diphosgene
DownStream 10
CAS#:370-50-3 flucofuron CAS#:75919-92-5 1-[4-(4-Nitroph... CAS#:755037-03-7 Regorafenib (BA... CAS#:284461-73-0 Sorafenib
CAS#:1130115-44-4 Donafenib (Sora... CAS#:330796-24-2 Hedgehog-IN-7d CAS#:369-77-7 Cloflucarban CAS#:70974-25-3 Hydantoin, 3-(4...
CAS#:86764-57-0 1,1-dibenzyl-3-... CAS#:86781-40-0 1,1-dibutyl-3-[...

HS Code	2929109000
Summary	2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

Bioorg. Med. Chem. 19(24) , 7603-1, (2011)

We report on Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt) inhibitory activities of a series of new 3'- and 5'-modified thymidine analogues including α- and β-derivatives. In addi...

Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors.

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p21 is a member of the cyclin kinase inhibitor family of proteins and plays pivotal roles in cellular proliferation as well as in the regulation of apoptosis, and thus has diverse functions in disease...

Sorafenib intermediate 3

Isocyanic Acid 4-Chloro-3-(trifluoromethyl)phenyl Ester

1-chloro-4-isocyanato-2-trifluoromethylbenzene

3-TRIFLUOROMETHYL-4-CHLORO-PHENYL ISOCYANATE

4-Cl-3CF3-phenyl isocyanate

4-Chloro-3-(trifluoromethyl)phenyl isocyanate

MFCD00013874

1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene

4-Chloro-3-(trifluoromethyl)phenylisocyanate

Benzene, 1-chloro-4-isocyanato-2-(trifluoromethyl)-