80724-19-2

80724-19-2 structure

Name: Tetramethylrhodamine-5-isothiocyanate
Chemical Name: 2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-isothiocyanatobenzoate
CAS Number: 80724-19-2
Molecular Formula: C₂₅H₂₁N₃O₃S
Molecular Weight: 443.51800
Catalog: Research Areas Cancer
Create Date: 2018-09-02 16:56:28
Modify Date: 2025-08-27 17:56:26
Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles[1][2].

Name	2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-isothiocyanatobenzoate
Synonyms	Xanthylium Tetramethylrhodamine-5-isothiocyanate 5-TRITC 5-TRITC,G isomer MFCD00467978

Description	Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Alayed KM, et al. Immunostaining for rapid diagnosis of acute promyelocytic leukemia with the tetramethylrhodamine-5-isothiocyanate-conjugated anti-promyelocytic leukemia monoclonal antibody PG-M3. Arch Pathol Lab Med. 2013 Nov;137(11):1669-73. [2]. Navarro SM, et al. Biodistribution of PLGA and PLGA/chitosan nanoparticles after repeat-dose oral delivery in F344 rats for 7 days. Ther Deliv. 2014 Nov;5(11):1191-201.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22;S24/25
RIDADR	NONH for all modes of transport