Name | 1-ethynylnaphthalene |
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Synonyms |
1-(ethynyl)naphthalene
1-naphthalene-acetylene Naphthalene,1-ethynyl naphthylacetylene (1-naphthyl)acetylene MFCD02093737 ethynyl-naphthalene |
Description | 1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1. |
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Related Catalog | |
Target |
P450 1B1[1] |
In Vitro | 1-Ethynylnaphthalene, selective inhibitor of cytochrome P450 IB1, does not affect 2-hydroxylation but inhibits 4-hydroxylation by 38%. At higher concentrations, 1-Ethynylnaphthalene inhibits 2-hydroxylation of 2-Hydroxylation of estradiol (E2) by ~30% and 4-hydroxylation of E2 by up to 80%[1]. |
References |
Density | 1.070 g/mL at 25ºC(lit.) |
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Boiling Point | 270.4ºC at 760 mmHg |
Molecular Formula | C12H8 |
Molecular Weight | 152.19200 |
Flash Point | 106.3ºC |
Exact Mass | 152.06300 |
LogP | 2.82110 |
Vapour Pressure | 0.0114mmHg at 25°C |
Index of Refraction | n20/D 1.6500(lit.) |
Storage condition | 2-8℃ |
Precursor 10 | |
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DownStream 10 | |
HS Code | 2902909090 |
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Summary | 2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0% |