| Name | 4-nitrophenyl-α-D-galactoside |
|---|---|
| Synonyms |
4-nitrophenyl-alpha-D-galactoside
4-Nitrophenyl β-D-galactopyranoside 1-O-[P-NITROPHENYL]-β-D-GALACTOPYRANOSE β-D-Galactopyranoside, 4-nitrophenyl (9CI) β-D-Galactopyranoside, 4-nitrophenyl MFCD00065050 p-Nitrophenyl .α.-D-galactopyranoside α-D-Galactopyranoside, 4-nitrophenyl p-Nitrophenyl α-D-galactopyranoside 4-Nitrophenyl α-D-galactopyranoside EINECS 231-343-6 p-Nitrophenyl β-D-galactopyranoside 4-Nitrophenyl a-D-galactopyranoside |
| Description | 4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Using 4-nitorophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0[1]. The digestion assays using 4-nitrophenyl (pNP) glycopyranosides as artificial substrates shows that yieldin liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 582.2±50.0 °C at 760 mmHg |
| Melting Point | 166-169ºC |
| Molecular Formula | C12H15NO8 |
| Molecular Weight | 301.249 |
| Flash Point | 305.9±30.1 °C |
| Exact Mass | 301.079773 |
| PSA | 145.20000 |
| LogP | -0.55 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.648 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
~%
7493-95-0 |
| Literature: Canadian Journal of Chemistry, , vol. 59, p. 314 - 320 |
|
~%
7493-95-0 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 589, p. 77,79 Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 311, p. 54,58 |
|
~%
7493-95-0 |
| Literature: Canadian Journal of Chemistry, , vol. 59, p. 314 - 320 |
|
~%
7493-95-0 |
| Literature: Canadian Journal of Chemistry, , vol. 59, p. 314 - 320 |
|
~%
7493-95-0 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 589, p. 77,79 Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 311, p. 54,58 |
| Precursor 5 | |
|---|---|
| DownStream 8 | |