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7493-95-0

7493-95-0 structure
7493-95-0 structure
  • Name: 4-Nitrophenyl α-D-galactopyranoside
  • Chemical Name: 4-nitrophenyl-α-D-galactoside
  • CAS Number: 7493-95-0
  • Molecular Formula: C12H15NO8
  • Molecular Weight: 301.249
  • Catalog: Biochemical Carbohydrate Monosaccharide
  • Create Date: 2018-12-05 14:56:29
  • Modify Date: 2024-01-02 14:28:21
  • 4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates[1].

Name 4-nitrophenyl-α-D-galactoside
Synonyms 4-nitrophenyl-alpha-D-galactoside
4-Nitrophenyl β-D-galactopyranoside
1-O-[P-NITROPHENYL]-β-D-GALACTOPYRANOSE
β-D-Galactopyranoside, 4-nitrophenyl (9CI)
β-D-Galactopyranoside, 4-nitrophenyl
MFCD00065050
p-Nitrophenyl .α.-D-galactopyranoside
α-D-Galactopyranoside, 4-nitrophenyl
p-Nitrophenyl α-D-galactopyranoside
4-Nitrophenyl α-D-galactopyranoside
EINECS 231-343-6
p-Nitrophenyl β-D-galactopyranoside
4-Nitrophenyl a-D-galactopyranoside
Description 4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates[1].
Related Catalog
In Vitro Using 4-nitorophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0[1]. The digestion assays using 4-nitrophenyl (pNP) glycopyranosides as artificial substrates shows that yieldin liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most[1].
References

[1]. Okamoto-Nakazato A. Implications of the galactosidase activity of yieldin in the regulatory mechanism of yield threshold that is fundamental to cell wall extension. Physiol Plant. 2018 Jun;163(2):259-266.

Density 1.6±0.1 g/cm3
Boiling Point 582.2±50.0 °C at 760 mmHg
Melting Point 166-169ºC
Molecular Formula C12H15NO8
Molecular Weight 301.249
Flash Point 305.9±30.1 °C
Exact Mass 301.079773
PSA 145.20000
LogP -0.55
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.648
Storage condition 2-8°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3

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7493-95-0 structure

7493-95-0

Literature: Canadian Journal of Chemistry, , vol. 59, p. 314 - 320

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7493-95-0 structure

7493-95-0

Literature: Justus Liebigs Annalen der Chemie, , vol. 589, p. 77,79 Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 311, p. 54,58

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7493-95-0 structure

7493-95-0

Literature: Canadian Journal of Chemistry, , vol. 59, p. 314 - 320

~%

7493-95-0 structure

7493-95-0

Literature: Canadian Journal of Chemistry, , vol. 59, p. 314 - 320

~%

7493-95-0 structure

7493-95-0

Literature: Justus Liebigs Annalen der Chemie, , vol. 589, p. 77,79 Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 311, p. 54,58