7493-95-0
7493-95-0 structure
- Name: 4-Nitrophenyl α-D-galactopyranoside
- Chemical Name: 4-nitrophenyl-α-D-galactoside
- CAS Number: 7493-95-0
- Molecular Formula: C12H15NO8
- Molecular Weight: 301.249
- Catalog: Biochemical Carbohydrate Monosaccharide
- Create Date: 2018-12-05 14:56:29
- Modify Date: 2026-07-01 16:20:43
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4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates[1].
| Name | 4-nitrophenyl-α-D-galactoside |
|---|---|
| Synonyms |
4-Nitrophenyl-^a-D-galactopyranoside
4-Nitrophenyl α-D-galacto PNP-ALPHA-GAL MFCD00065050 oside 4-Nitrophenyl-ɑ-D-galactopyranoside pyran 4-Nitrobenzene- α- D-galactopyranoside 4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE p-NITROPHENYL-a-D-GLUCOPYRANOSIDE extrapure (2R,3R,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol p-Nitrophenyl a-D-Galactopyranoside extrapure Nitrophenyl-α-D-Glucoyranoside 4-nitrophenyl-alpha-D-galactoside α-D-Galactopyranoside, 4-nitropheny 4-Nitrophenyl α-D-Galactopyranoside/4-Nitrophenyl-α-D-galactopyranoside/Gal-α-pNP P-NITROPHENYL-ALPHA-D-GALACTOYRANOSIDE 4-Nitrophenyl alpha-D-Galactopyranoside [Substrate for alpha-D-Galactosidase] Gal1-α-PNP 4-Nitrophenyl α-D-Galactopyranoside [Substrate for α-D-Galactosidase] P-Nitrophenyl-Alpha-D-GalactopyranosideA.R P-NITROPHENYL ALPHA-D-GALACTOPYRANOSIDE 4’-nitrophenyl-b-D-galactopyranoside p-Nitrophenyl .α.-D-galactopyranoside 4-nitrophenyl α-D-galactopyranoside(p-) p-Nitrophenyl α-D-galactopyranoside P-NITROPHENYL A-D-GALACTOPYRANOSIDE 4-Nitrophenyl a-D-galactopyranoside 4-Nitrophenyl alpha-D-Galactopyranoside 4-Nitrophenyl β-D-galactopyranoside 4-Nitrophenyl alpha-D-galactopyranoside alpha-galactosidase substrate 4-Nitrophenylα-D-Galactopyranoside[Substrateforα-D-Galactosidase]> β-D-Galactopyranoside, 4-nitrophenyl (9CI) NITROPHENYL-A-D-GALACTOPYRANOSIDE, 4 β-D-Galactopyranoside, 4-nitrophenyl 4-Nitrophenyl α-D-galactopyranoside, 10 mM in DMSO α-Methyl-β-alanine EINECS 231-343-6 p-Nitrophenyl β-D-galactopyranoside P-NITROPHENYL ALPHA-D-GALACTOSIDE p-Nitrophenyl-D-galactoyranoside 4-Nitrophenyl α-D-galacto-pyran-oside,p-Nitrophenyl α-D-galacto-pyran-oside GAL1-A-PNP PNP ALPHA-D-GALACTOPYRANOSIDE p-Nitrophenyl α-D-Galactopyranoside 4-Nitrophenyl-α-D-galactopyranoside PNP-ALPHA-D-GAL 1-O-[P-NITROPHENYL]-β-D-GALACTOPYRANOSE [Substrate for alpha-D-Galactosidase] 4-nitrophenyl alpha-dextro-galactopyranoside 4-Nitrophenyla-D-galactopyranoside 5-Nitrophenyl β-D-galactopyranoside 4-Nitrophenyl α-D-galactopyranoside PNPG Gal-a-PNP α-D-Galactopyranoside, 4-nitrophenyl 4-nitrophenyl-à-d-galactopyranoside alpha-d-galactopyranoside,4-nitrophenyl 4-Nitrophenyl α- D -galactopyranoside 4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE //BP |
| Description | 4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Using 4-nitorophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0[1]. The digestion assays using 4-nitrophenyl (pNP) glycopyranosides as artificial substrates shows that yieldin liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 582.2±50.0 °C at 760 mmHg |
| Melting Point | 166-169ºC |
| Molecular Formula | C12H15NO8 |
| Molecular Weight | 301.249 |
| Flash Point | 305.9±30.1 °C |
| Exact Mass | 301.079773 |
| PSA | 145.20000 |
| LogP | -0.55 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.648 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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7493-95-0 |
| Literature: Canadian Journal of Chemistry, , vol. 59, p. 314 - 320 |
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7493-95-0 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 589, p. 77,79 Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 311, p. 54,58 |
|
~%
7493-95-0 |
| Literature: Canadian Journal of Chemistry, , vol. 59, p. 314 - 320 |
|
~%
7493-95-0 |
| Literature: Canadian Journal of Chemistry, , vol. 59, p. 314 - 320 |
|
~%
7493-95-0 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 589, p. 77,79 Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 311, p. 54,58 |
| Precursor 5 | |
|---|---|
| DownStream 8 | |
