Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Neosolaniol
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Neosolaniol
Price: ￥20158.0/25mg ￥6318.0/5mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Trichothec-9-ene-3,4,8,15-tetrol,12,13-epoxy-, 4,15-diacetate, (3a,4b,8a)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

36519-25-2

36519-25-2 structure

Name: Neosolaniol
Chemical Name: Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate
CAS Number: 36519-25-2
Molecular Formula: C₁₉H₂₆O₈
Molecular Weight: 382.405
Catalog: analytical chemistry Standard Food and cosmetics standards
Create Date: 2018-02-05 08:00:00
Modify Date: 2024-01-08 18:26:15
Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp[1]. Neosolaniol evokes robust anorectic response[2].

Name	Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate
Synonyms	Trichothec-9-ene, 12,13-epoxy-4-β,15-diacetoxy-3-α,8-α-dihydroxy- 4-β,15-Diacetoxy-3-α,8-α-dihydroxy-12,13-epoxytrichothec-9-ene Trichothec-9-ene-3-α,4-β,8-α,15-tetrol, 12,13-epoxy-, 4,15-diacetate (3α,4β,8α)-3,8-Dihydroxy-12,13-epoxytrichothec-9-ene-4,15-diyl diacetate Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate, (3α,4β,8α)- Solaniol (van) 8-HYDROXYDIACETOXYSCIRPENOL neosolaniol solution Neosalaniol NEOSOLANIOL

Description	Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp[1]. Neosolaniol evokes robust anorectic response[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. McCormick SP, et al. Trichothecenes: from simple to complex mycotoxins. Toxins (Basel). 2011 Jul;3(7):802-14. [2]. Zhang J, et al. Comparison of Anorectic Potencies of Type A Trichothecenes T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol. Toxins (Basel). 2018 Apr 29;10(5).

Density	1.4±0.1 g/cm3
Boiling Point	515.9±50.0 °C at 760 mmHg
Melting Point	171.5°C
Molecular Formula	C₁₉H₂₆O₈
Molecular Weight	382.405
Flash Point	180.2±23.6 °C
Exact Mass	382.162781
PSA	114.82000
LogP	-0.07
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.578
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YD0080000

CHEMICAL NAME :: Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate

CAS REGISTRY NUMBER :: 36519-25-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H26-O8

MOLECULAR WEIGHT :: 382.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S124,1984 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JJEMAG Japanese Journal of Experimental Medicine. (Kinokuniya Book-Stores of America Co., Ltd., West Bldg., Japan Cultural and Trade Center, 1581 Webster St., San Francisco, CA 94115) V.7- 1928- Volume(issue)/page/year: 42,187,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 24,985,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 24870 ug/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Behavioral - muscle weakness Behavioral - food intake (animal)

REFERENCE :: AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 35,636,1978

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300 + H310 + H330
Precautionary Statements	P260-P264-P280-P284-P301 + P310-P302 + P350
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+,Xn,F
Risk Phrases	26/27/28-36-20/21/22-11
Safety Phrases	22-36/37/39-45-36/37-16-26
RIDADR	UN 2811 6.1/PG 1
WGK Germany	3
RTECS	YD0080000
Packaging Group	I
Hazard Class	6.1(a)

77620-47-4

~38%

36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

81331-38-6

~14%

36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

2270-40-8

36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

81331-38-6

36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

Precursor 4
77620-47-4 81331-38-6 2270-40-8 36519-25-2
DownStream 9
36519-25-2 65725-06-6 65041-92-1 68165-53-7
81331-40-0 81331-42-2 81331-43-3 77620-58-7
77620-59-8

36519-25-2	65041-92-1
77620-53-2	1158522-08-7
940364-43-2	134104-43-1
2229428-05-9	2171929-40-9
2228372-36-7	131615-57-1
6906-52-1	930439-75-1
1018584-77-4