Neosolaniol

Modify Date: 2024-01-08 18:26:15

Neosolaniol structure	Common Name	Neosolaniol
	CAS Number	36519-25-2	Molecular Weight	382.405
	Density	1.4±0.1 g/cm3	Boiling Point	515.9±50.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₂₆O₈	Melting Point	171.5°C
	MSDS	Chinese USA	Flash Point	180.2±23.6 °C
	Symbol	GHS06	Signal Word	Danger

Use of Neosolaniol

Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp[1]. Neosolaniol evokes robust anorectic response[2].

Name	Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate
Synonym	More Synonyms

Description	Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp[1]. Neosolaniol evokes robust anorectic response[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. McCormick SP, et al. Trichothecenes: from simple to complex mycotoxins. Toxins (Basel). 2011 Jul;3(7):802-14. [2]. Zhang J, et al. Comparison of Anorectic Potencies of Type A Trichothecenes T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol. Toxins (Basel). 2018 Apr 29;10(5).

Description

Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp[1]. Neosolaniol evokes robust anorectic response[2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. McCormick SP, et al. Trichothecenes: from simple to complex mycotoxins. Toxins (Basel). 2011 Jul;3(7):802-14.

[2]. Zhang J, et al. Comparison of Anorectic Potencies of Type A Trichothecenes T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol. Toxins (Basel). 2018 Apr 29;10(5).

Density	1.4±0.1 g/cm3
Boiling Point	515.9±50.0 °C at 760 mmHg
Melting Point	171.5°C
Molecular Formula	C₁₉H₂₆O₈
Molecular Weight	382.405
Flash Point	180.2±23.6 °C
Exact Mass	382.162781
PSA	114.82000
LogP	-0.07
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.578
Storage condition	2-8°C

Neosolaniol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YD0080000

CHEMICAL NAME :: Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate

CAS REGISTRY NUMBER :: 36519-25-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H26-O8

MOLECULAR WEIGHT :: 382.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S124,1984 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JJEMAG Japanese Journal of Experimental Medicine. (Kinokuniya Book-Stores of America Co., Ltd., West Bldg., Japan Cultural and Trade Center, 1581 Webster St., San Francisco, CA 94115) V.7- 1928- Volume(issue)/page/year: 42,187,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 24,985,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 24870 ug/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Behavioral - muscle weakness Behavioral - food intake (animal)

REFERENCE :: AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 35,636,1978

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300 + H310 + H330
Precautionary Statements	P260-P264-P280-P284-P301 + P310-P302 + P350
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+,Xn,F
Risk Phrases	26/27/28-36-20/21/22-11
Safety Phrases	22-36/37/39-45-36/37-16-26
RIDADR	UN 2811 6.1/PG 1
WGK Germany	3
RTECS	YD0080000
Packaging Group	I
Hazard Class	6.1(a)

4,15-Bis(acetyl...

CAS#:77620-47-4

~38%

Neosolaniol

CAS#:36519-25-2

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

4β,15-diacetoxy...

CAS#:81331-38-6

~14%

Neosolaniol

CAS#:36519-25-2

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

Diacetoxyscirpenol

CAS#:2270-40-8

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

Neosolaniol

CAS#:36519-25-2

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

4β,15-diacetoxy...

CAS#:81331-38-6

Neosolaniol

CAS#:36519-25-2

Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 579 - 589

Precursor 4
CAS#:77620-47-4 4,15-Bis(acetyl... CAS#:81331-38-6 4β,15-diacetoxy... CAS#:2270-40-8 Diacetoxyscirpenol CAS#:36519-25-2 Neosolaniol
DownStream 9
CAS#:36519-25-2 Neosolaniol CAS#:65725-06-6 T-2 TETRAOL TET... CAS#:65041-92-1 neosolaniol CAS#:68165-53-7 Trichothec-9-en...
CAS#:81331-40-0 3α,8β-bis-O-(2-... CAS#:81331-42-2 15-acetoxy-4β-(... CAS#:81331-43-3 4β,15-bis(metha... CAS#:77620-58-7 Trichothec-9-en...
CAS#:77620-59-8 4β,15-bis(metha...

Toxicity induced by F. poae-contaminated feed and the protective effect of Montmorillonite supplementation in broilers.

Food Chem. Toxicol. 74 , 120-30, (2014)

The T-2 and HT-2 toxins, the main metabolites of Fusarium poae, induce toxicity in broilers and accumulate in tissues. Consequently, during the breeding process of broilers, diets are frequently suppl...

Key glycolytic enzyme activities of skeletal muscle are decreased under fed and fasted states in mice with knocked down levels of Shc proteins.

PLoS ONE 10(4) , e0124204, (2015)

Shc proteins interact with the insulin receptor, indicating a role in regulating glycolysis. To investigate this idea, the activities of key glycolytic regulatory enzymes and metabolites levels were m...

Hooking She3p onto She2p for myosin-mediated cytoplasmic mRNA transport.

Proc. Natl. Acad. Sci. U. S. A. 112(1) , 142-7, (2015)

The segregation of approximately two dozen distinct mRNAs from yeast mother to daughter cell cytoplasm is a classical paradigm for eukaryotic mRNA transport. The information for transport resides in a...

Trichothec-9-ene, 12,13-epoxy-4-β,15-diacetoxy-3-α,8-α-dihydroxy-

4-β,15-Diacetoxy-3-α,8-α-dihydroxy-12,13-epoxytrichothec-9-ene

Trichothec-9-ene-3-α,4-β,8-α,15-tetrol, 12,13-epoxy-, 4,15-diacetate

(3α,4β,8α)-3,8-Dihydroxy-12,13-epoxytrichothec-9-ene-4,15-diyl diacetate

Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate, (3α,4β,8α)-

Solaniol (van)

8-HYDROXYDIACETOXYSCIRPENOL

neosolaniol solution

Neosalaniol

NEOSOLANIOL

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Neosolaniol
Price: ￥20158.0/25mg ￥6318.0/5mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Trichothec-9-ene-3,4,8,15-tetrol,12,13-epoxy-, 4,15-diacetate, (3a,4b,8a)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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