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758-17-8

758-17-8 structure
758-17-8 structure
  • Name: N-FORMYL-N-METHYLHYDRAZINE
  • Chemical Name: N-amino-N-methylformamide
  • CAS Number: 758-17-8
  • Molecular Formula: C2H6N2O
  • Molecular Weight: 74.08180
  • Create Date: 2016-06-10 23:22:18
  • Modify Date: 2025-08-26 17:28:54
Name N-amino-N-methylformamide
Synonyms Hydrazine,1-formyl-1-methyl
N-METHYL-N-FORMYLHYDRAZINE
1-Methyl-1-formylhydrazide
Methylformylhydrazine
2-Methyl-2-formylhydrazine
1-Formyl-1-methylhydrazin
Formic acid,methylhydrazide
N-amino-N-methyl-formamide
Formic acid,1-methylhydrazide
N-methylformic hydrazide
N-formyl-N-methylhydrazine
1-formyl-1-methylhydrazine
1-methyl-1-formyl-hydrazine
1-Methylformylhydrazine
Density 1.061g/cm3
Boiling Point 118.6ºC at 760 mmHg
Melting Point 219-222 °C
Molecular Formula C2H6N2O
Molecular Weight 74.08180
Flash Point 25.5ºC
Exact Mass 74.04800
PSA 46.33000
LogP 0.28450
Index of Refraction 1.45
Storage condition 2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LQ8940000
CHEMICAL NAME :
Formic acid, methylhydrazide
CAS REGISTRY NUMBER :
758-17-8
LAST UPDATED :
199612
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C2-H6-N2-O
MOLECULAR WEIGHT :
74.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
118 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Liver - other changes Kidney, Ureter, Bladder - other changes
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
14 mg/kg/62W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg/40W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - hamster
DOSE/DURATION :
6100 mg/kg/80W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7840 mg/kg/70W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3360 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Lungs, Thorax, or Respiration - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3158 mg/kg/94W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Lungs, Thorax, or Respiration - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3920 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - other reproductive system tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
64 mg/kg/80W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - lymphoma, including Hodgkin's disease
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
84 mg/kg/70W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Gastrointestinal - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
187 mg/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - lymphoma, including Hodgkin's disease
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
158 mg/kg/79W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - lymphoma, including Hodgkin's disease

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 umol/plate
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 26,155,1983
Hazard Codes T+
60-34-4 structure

60-34-4

109-94-4 structure

109-94-4

~76%

758-17-8 structure

758-17-8

155106-68-6 structure

155106-68-6

Literature: Delalu, Henri; Sabate, Carlos Miro Chemistry - An Asian Journal, 2012 , vol. 7, # 4 p. 715 - 724
64-18-6 structure

64-18-6

60-34-4 structure

60-34-4

~90%

758-17-8 structure

758-17-8

Literature: Werner, Wolfgang; Depreux, Patrick Journal of Chemical Research, Miniprint, 1980 , # 11 p. 4513 - 4521
16694-46-5 structure

16694-46-5

60-34-4 structure

60-34-4

~%

758-17-8 structure

758-17-8

Literature: Kohn,H.; Olofson,R.A. Journal of Organic Chemistry, 1972 , vol. 37, # 22 p. 3504 - 3509
60-34-4 structure

60-34-4

109-94-4 structure

109-94-4

~%

758-17-8 structure

758-17-8

Literature: Pedersen,C.T. Acta Chemica Scandinavica (1947-1973), 1964 , vol. 18, p. 2199 - 2200
107-31-3 structure

107-31-3

60-34-4 structure

60-34-4

~%

758-17-8 structure

758-17-8

Literature: Dorn,H. et al. Chemische Berichte, 1965 , vol. 98, p. 3377 - 3384 Show Details Zinner,G.; Gebhardt,U. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1971 , vol. 304, p. 706 - 712
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title: CAS No. 758-17-8 | Chemsrc address: https://m.chemsrc.com/en/baike/760015.html

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