172531-37-2

172531-37-2 structure

Name: 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid
Chemical Name: 11-Azido-3,6,9-trioxaundecanoic Acid
CAS Number: 172531-37-2
Molecular Formula: C₈H₁₅N₃O₅
Molecular Weight: 233.22200
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-08-21 14:57:18
Modify Date: 2024-01-01 17:13:49
PROTAC Linker 14 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 14 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	11-Azido-3,6,9-trioxaundecanoic Acid
Synonyms	Azido-PEG3-carboxylate 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid

Description	PROTAC Linker 14 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 14 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.