2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid

Modify Date: 2025-08-24 18:30:51

2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid Structure
2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid structure
Common Name 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid
CAS Number 172531-37-2 Molecular Weight 233.22200
Density N/A Boiling Point N/A
Molecular Formula C8H15N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid


PROTAC Linker 14 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 14 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name 11-Azido-3,6,9-trioxaundecanoic Acid
Synonym More Synonyms

  Biological Activity

Description PROTAC Linker 14 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 14 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C8H15N3O5
Molecular Weight 233.22200
Exact Mass 233.10100
PSA 114.74000
Index of Refraction 1.47

 Synthetic Route

 Synonyms

Azido-PEG3-carboxylate
2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid
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