100750-39-8

100750-39-8 structure

Name: N-Acetyl-3-acetoxy-5-phenylpyrrole
Chemical Name: (1-acetyl-5-phenylpyrrol-3-yl) acetate
CAS Number: 100750-39-8
Molecular Formula: C₁₄H₁₃NO₃
Molecular Weight: 243.25800
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-12-25 09:55:31
Modify Date: 2024-01-10 17:49:25
APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research[1].

Name	(1-acetyl-5-phenylpyrrol-3-yl) acetate
Synonyms	N-ACETYL-3-ACETOXY-5-PHENYLPYRROLE 1-Acetyl-5-phenyl-1H-pyrrol-3-ol Acetate 4-acetoxy-1-acetyl-2-phenyl-pyrrole

Description	APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Metabolic Enzyme/Protease >> Aldose Reductase Research Areas >> Metabolic Disease
References	[1]. Zhi-Ming Xiu, et al. 1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate: An aldose reductase inhibitor for the treatment of diabetic nephropathy. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4482-4487.

856343-07-2

100750-39-8

Literature: Chemische Berichte, , vol. 63, p. 2870,2874

856097-96-6

108-24-7

100750-39-8

Literature: Chemische Berichte, , vol. 63, p. 2870,2874

108-24-7

100750-39-8

Literature: Chemische Berichte, , vol. 63, p. 2870,2874

Precursor 3
856343-07-2 856097-96-6 108-24-7
DownStream 0