2491-38-5
- Name: 2-Bromo-4'-hydroxyacetophenone
- Chemical Name: 2-Bromo-4'-hydroxyacetophenone
- CAS Number: 2491-38-5
- Molecular Formula: C8H7BrO2
- Molecular Weight: 215.044
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
- Create Date: 2018-06-21 13:45:24
- Modify Date: 2026-07-01 21:53:45
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2-Bromo-4'-hydroxyacetophenone a PTP1B inhibitor, with a Ki of 42 μM[1].
| Name | 2-Bromo-4'-hydroxyacetophenone |
|---|---|
| Synonyms |
Aipha-BroMo-4-hydroxyacetophenone
(+)-alpha-isolupanine 4-(Bromoacetyl)phenol PTP INHIBITOR I 2-Brom-1-(4-hydroxyphenyl)ethan-1-on 4-Hydroxyphenacyl Bromide Butrol 1130 Butrol 2-Bromo-1-(4-hydroxyphenyl)ethanone p-Hydroxy α-Bromoacetophenone 2-Bromo-4''-hydroxyacetophenone, 10 mM in DMSO MFCD00072424 4-HYDROXYPHENACYL BR BUSAN1130 SHP-1 Inhibitor II 2-Bromo-4’-hydroxyacetophenone PTP Inhibitor I - - Calbiochem Ethanone, 2-bromo-1-(4-hydroxyphenyl) 4-Hydroxy α-Bromoacetophenone BROMOHYDROXYACETOPHENONE A-BROMO-4-HYDROXY ACETOPHENONE 2-bromo-1-(4-hydroxyphenyl)ethan-1-one PROTEIN TYROSINE PHOSPHATASE INHIBITOR I 4-HYDROXY A-BROMOACETOPHENONE 1-(4-hydroxyphenyl)-2-bromoethanone EINECS 219-655-0 2-Bromo-4'-hydroxyacetophenone > 2-BROMO-1-(4-HYDROXY-PHENYL)-ETHANONE p-Hydroxyphenacyl BroMide Cyclohexane Impurity 5 BHAP 2-Bromo-4'-Hydroxy-Acetophenone 2-Bromo-4-Hydroxyacetophenone 2'-BROMO-4'-HYDROXYACETOPHENONE α-broMo p-hydroxyacetophenone 2-Bromo-1-(4-hydroxyphenyl)ethanone p-Hydroxyphenacyl bromide ALPHA-BROMO-4-HYDROXYACETOPHENONE 2-Bromo-4'-hydroxyacetophenone, 2-Bromo-1-(4-hydroxyphenyl)ethan-1-one BUSAN90 Alpha broMine generation of hydroxy acetophenone Isavuconazole Impurity N16 4-HYDROXYPHENACYL BROMIDE 4-Hydroxy-alpha-bromoacetophenone 2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) 2-Bromo-4''-hydroxyacetophenone α-Bromo-4-hydroxyacetophenone |
| Description | 2-Bromo-4'-hydroxyacetophenone a PTP1B inhibitor, with a Ki of 42 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 42 μM (PTP1B)[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 338.7±17.0 °C at 760 mmHg |
| Melting Point | 123-126°C |
| Molecular Formula | C8H7BrO2 |
| Molecular Weight | 215.044 |
| Flash Point | 158.6±20.9 °C |
| Exact Mass | 213.962936 |
| PSA | 37.30000 |
| LogP | 1.95 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.609 |
| Storage condition | -70°C |
CHEMICAL IDENTIFICATION
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| Hazard Codes | C: Corrosive; |
|---|---|
| Risk Phrases | 22-36 |
| Safety Phrases | 26 |
| RIDADR | UN 1760 |
| Packaging Group | III |
| HS Code | 2914700090 |
|
~95%
2491-38-5 |
| Literature: San Miguel, Veronica; Bochet, Christian G.; Del Campo, Aranzazu Journal of the American Chemical Society, 2011 , vol. 133, # 14 p. 5380 - 5388 |
|
~93%
2491-38-5 |
| Literature: Rodygin, M. Yu.; Mikhailov, V. A.; Savelova, V. A. Russian Journal of Organic Chemistry, 1994 , vol. 30, # 6.1 p. 881 - 887 Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 6 p. 827 - 832 |
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| Literature: US2002/55527 A1, ; |
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| Literature: Journal of the American Chemical Society, , vol. 71, p. 2652,2654 |
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| Literature: EP2216051 A1, ; |
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| Literature: Journal of the American Chemical Society, , vol. 71, p. 2652,2654 |
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| Literature: Nippon Kagaku Zasshi, , vol. 80, p. 212 Chem.Abstr., , p. 4406 |
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| Literature: US2838570 , ; US2838570 , ; |
|
~14%
2491-38-5 |
| Literature: Bulletin of the Chemical Society of Japan, , vol. 65, # 1 p. 295 - 297 |
| Precursor 8 | |
|---|---|
| DownStream 10 | |
![[[p-(2-methoxyethyl)phenoxy]methyl]oxirane structure](https://image.chemsrc.com/caspic/144/56718-70-8.png)
![4-[2-(bromomethyl)-1,3-dioxolan-2-yl]phenol structure](https://image.chemsrc.com/caspic/446/182296-61-3.png)
| HS Code | 2914700090 |
|---|---|
| Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |