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74058-71-2

74058-71-2 structure
74058-71-2 structure
  • Name: Macamide B
  • Chemical Name: N-benzylhexadecanamide
  • CAS Number: 74058-71-2
  • Molecular Formula: C23H39NO
  • Molecular Weight: 345.56200
  • Catalog: Natural product Alkaloid
  • Create Date: 2018-03-23 08:00:00
  • Modify Date: 2024-01-06 18:45:32
  • N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH).

Name N-benzylhexadecanamide
Synonyms N-benzylpalmitamide
N-Benzyl-palmitinamid
N-benzyl-hexadecanamide
N-hexadecanoyl benzylamine
N-Benzyl-palmitamid
N-benzylhexylhexadecanamide
Description N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH).
Related Catalog
Target

FAAH[1]

In Vitro N-Benzylpalmitamide is an inhibitor of fatty acid amide hydrolase (FAAH), and shows 24.8% and 43.8% inhibition on FAAH at 10 μM and 500 μM, respectively[1].
References

[1]. Wu H, et al. Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition. Bioorg Med Chem. 2013 Sep 1;21(17):5188-97.

Melting Point 95-96℃
Molecular Formula C23H39NO
Molecular Weight 345.56200
Exact Mass 345.30300
PSA 32.59000
LogP 7.62440
Hazard Codes Xi

~89%

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Literature: Komura, Kenichi; Nakano, Yu; Koketsu, Mamoru Green Chemistry, 2011 , vol. 13, # 4 p. 828 - 831

~86%

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Literature: Wu, Hui; Kelley, Charles J.; Pino-Figueroa, Alejandro; Vu, Huyen D.; Maher, Timothy J. Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 17 p. 5188 - 5197

~88%

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Literature: Ranu, Brindaban C.; Dutta, Pinak Synthetic Communications, 2003 , vol. 33, # 2 p. 297 - 301

~95%

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Literature: Nagao, Yoshimitsu; Seno, Kaoru; Kawabata, Kohji; Miyasaka, Tadayo; Takao, Sachiko; Fujita, Eiichi Tetrahedron Letters, 1980 , vol. 21, p. 841 - 844 Title/Abstract View citing articles Show Details Nagao, Yoshimitsu; Seno, Kaoru; Kawabata, Kohji; Miyasaka, Tadao; Takao, Sachiko; Fujita, Eiichi Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 7 p. 2687 - 2699

~96%

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Literature: Feairheller, S. H.; Bistline, R. G.; Bilyk, A.; Dudley, R. L.; Kozempel, M. F.; Haas, M. J. Journal of the American Oil Chemists' Society, 1994 , vol. 71, # 8 p. 863 - 866

~97%

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Literature: Miyasaka, Tadayo; Noguchi, Shunsaku Chemistry Letters, 1985 , p. 701 - 704

~%

74058-71-2 structure

74058-71-2

Literature: Nagao, Yoshimitsu; Seno, Kaoru; Kawabata, Kohji; Miyasaka, Tadayo; Takao, Sachiko; Fujita, Eiichi Tetrahedron Letters, 1980 , vol. 21, p. 841 - 844

~%

74058-71-2 structure

74058-71-2

Literature: Miyasaka, Tadayo; Noguchi, Shunsaku Chemistry Letters, 1985 , p. 701 - 704

~%

74058-71-2 structure

74058-71-2

Literature: Bowen; Smith Journal of the American Chemical Society, 1940 , vol. 62, p. 3522