82475-00-1

82475-00-1 structure

Name: 2',5,6',7-Tetrahydroxyflavone
Chemical Name: 2-(2,6-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
CAS Number: 82475-00-1
Molecular Formula: C₁₅H₁₀O₆
Molecular Weight: 286.23600
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2016-05-13 02:21:01
Modify Date: 2024-04-02 17:43:54
5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM[1].

Name	2-(2,6-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
Synonyms	4H-1-Benzopyran-4-one,2-(2,6-dihydroxyphenyl)-5,7-dihydroxy 5,7,2',6'-Tetrahydroxyflavone

Description	5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Metabolic Disease
Target	CYP3A4:7.8 μM (IC50)
References	[1]. Ji-Yeon Kim, et al. Effects of flavonoids isolated from Scutellariae radix on cytochrome P-450 activities in human liver microsomes. J Toxicol Environ Health A. 2002 Mar;65(5-6):373-81.