2',5,6',7-Tetrahydroxyflavone

Modify Date: 2024-04-02 17:43:54

2',5,6',7-Tetrahydroxyflavone Structure
2',5,6',7-Tetrahydroxyflavone structure
Common Name 2',5,6',7-Tetrahydroxyflavone
CAS Number 82475-00-1 Molecular Weight 286.23600
Density 1.654g/cm3 Boiling Point 589ºC at 760 mmHg
Molecular Formula C15H10O6 Melting Point N/A
MSDS N/A Flash Point 228.9ºC

 Use of 2',5,6',7-Tetrahydroxyflavone


5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM[1].

 Names

Name 2-(2,6-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
Synonym More Synonyms

 2',5,6',7-Tetrahydroxyflavone Biological Activity

Description 5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM[1].
Related Catalog
Target

CYP3A4:7.8 μM (IC50)

References

[1]. Ji-Yeon Kim, et al. Effects of flavonoids isolated from Scutellariae radix on cytochrome P-450 activities in human liver microsomes. J Toxicol Environ Health A. 2002 Mar;65(5-6):373-81.  

 Chemical & Physical Properties

Density 1.654g/cm3
Boiling Point 589ºC at 760 mmHg
Molecular Formula C15H10O6
Molecular Weight 286.23600
Flash Point 228.9ºC
Exact Mass 286.04800
PSA 111.13000
LogP 2.28240
Index of Refraction 1.767

 Synonyms

4H-1-Benzopyran-4-one,2-(2,6-dihydroxyphenyl)-5,7-dihydroxy
5,7,2',6'-Tetrahydroxyflavone