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9005-35-0

9005-35-0 structure
9005-35-0 structure
  • Name: Calcium alginate
  • Chemical Name: Alginic Acid Calcium Salt
  • CAS Number: 9005-35-0
  • Molecular Formula: C36H42Ca3O36
  • Molecular Weight: 1170.93000
  • Catalog: API Blood system medication Hemostatic drug
  • Create Date: 2018-09-06 15:23:21
  • Modify Date: 2024-01-02 16:13:52
  • Calcium alginate is a biopolymer that can be used for developing oral drug-delivery systems[1]. Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media[2].

Name Alginic Acid Calcium Salt
Synonyms calcium,(2S,3S,4S,5S,6R)-6-[(2R,3S,4R,5S,6R)-2-carboxy-6-[(2R,3S,4R,5S,6R)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate
MFCD00143567
Description Calcium alginate is a biopolymer that can be used for developing oral drug-delivery systems[1]. Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media[2].
Related Catalog
In Vitro Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media. This enables the hydrogel to absorb and release aqueous solutions at certain ranges of pH values. By absorbing an aqueous solution containing a drug, an active drug release can be triggered at a specified range of pH value[2]. Calcium alginate is a biodegradable gel-transforming agent widely used for nasal packing. It can reduce pain and improve comfort[3].
References

[1]. Demitri C, et al. Encapsulation of Lactobacillus kefiri in alginate microbeads using a double novel aerosol technique. Mater Sci Eng C Mater Biol Appl. 2017;77:548-555.

[2]. Chengzhi Hu, et al. Electrosynthesis of magnetoresponsive microrobot for targeted drug delivery using calcium alginate. Annu Int Conf IEEE Eng Med Biol Soc. 2016;2016:2111-2114.

[3]. Park DY, et al. Comparison of calcium alginate and carboxymethyl cellulose for nasal packing after endoscopic sinus surgery: a prospective, randomised, controlled single-blinded trial. Clin Otolaryngol. 2016;41(3):234-240.

Density 2.1173 g/cm3
Molecular Formula C36H42Ca3O36
Molecular Weight 1170.93000
Exact Mass 1170.03000
PSA 511.32000

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AZ5810000
CHEMICAL NAME :
Alginic acid, calcium salt
CAS REGISTRY NUMBER :
9005-35-0
LAST UPDATED :
199701

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1407 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. Volume(issue)/page/year: 53A,381,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
64 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. Volume(issue)/page/year: 53A,381,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83092 No. of Facilities: 47 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 94 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83092 No. of Facilities: 643 (estimated) No. of Industries: 16 No. of Occupations: 7 No. of Employees: 3968 (estimated)
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AZ5820000