Calcium alginate

Modify Date: 2024-01-02 16:13:52

Calcium alginate structure	Common Name	Calcium alginate
	CAS Number	9005-35-0	Molecular Weight	1170.93000
	Density	2.1173 g/cm3	Boiling Point	N/A
	Molecular Formula	C₃₆H₄₂Ca₃O₃₆	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of Calcium alginate

Calcium alginate is a biopolymer that can be used for developing oral drug-delivery systems[1]. Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media[2].

Name	Alginic Acid Calcium Salt
Synonym	More Synonyms

Description	Calcium alginate is a biopolymer that can be used for developing oral drug-delivery systems[1]. Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media. This enables the hydrogel to absorb and release aqueous solutions at certain ranges of pH values. By absorbing an aqueous solution containing a drug, an active drug release can be triggered at a specified range of pH value[2]. Calcium alginate is a biodegradable gel-transforming agent widely used for nasal packing. It can reduce pain and improve comfort[3].
References	[1]. Demitri C, et al. Encapsulation of Lactobacillus kefiri in alginate microbeads using a double novel aerosol technique. Mater Sci Eng C Mater Biol Appl. 2017;77:548-555. [2]. Chengzhi Hu, et al. Electrosynthesis of magnetoresponsive microrobot for targeted drug delivery using calcium alginate. Annu Int Conf IEEE Eng Med Biol Soc. 2016;2016:2111-2114. [3]. Park DY, et al. Comparison of calcium alginate and carboxymethyl cellulose for nasal packing after endoscopic sinus surgery: a prospective, randomised, controlled single-blinded trial. Clin Otolaryngol. 2016;41(3):234-240.

Density	2.1173 g/cm3
Molecular Formula	C₃₆H₄₂Ca₃O₃₆
Molecular Weight	1170.93000
Exact Mass	1170.03000
PSA	511.32000

Calcium alginate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AZ5810000

CHEMICAL NAME :: Alginic acid, calcium salt

CAS REGISTRY NUMBER :: 9005-35-0

LAST UPDATED :: 199701

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1407 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. Volume(issue)/page/year: 53A,381,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 64 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. Volume(issue)/page/year: 53A,381,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83092 No. of Facilities: 47 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 94 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83092 No. of Facilities: 643 (estimated) No. of Industries: 16 No. of Occupations: 7 No. of Employees: 3968 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AZ5820000

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MFCD00143567