10391-08-9
10391-08-9 structure
- Name: macrocalin A
- Chemical Name: (3R,3aR,6aS,8aS,11R,13aS,13bS)-3-hydroxy-4,4-dimethyl-10-methylenedecahydro-1H,8H-8a,11-methanocyclohepta[c]furo[3,4-e]chromene-8,9(10H)-dione
- CAS Number: 10391-08-9
- Molecular Formula: C20H26O5
- Molecular Weight: 346.417
- Catalog: Natural product Moss
- Create Date: 2016-10-27 08:19:52
- Modify Date: 2025-08-27 15:20:03
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(-)-Isodocarpin (Isodocarpin), a diterpenoid, is a potent melanogenesis inhibitor with an IC50 of 0.19 μM in B16 4A5 cells. (-)-Isodocarpin inhibits the expression of tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA[1].
| Name | (3R,3aR,6aS,8aS,11R,13aS,13bS)-3-hydroxy-4,4-dimethyl-10-methylenedecahydro-1H,8H-8a,11-methanocyclohepta[c]furo[3,4-e]chromene-8,9(10H)-dione |
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| Synonyms |
(1S,4S,8R,9R,12S,13S,16R)-9-Hydroxy-7,7-dimethyl-17-methylene-3,10-dioxapentacyclo[14.2.1.0.0.0]nonadecane-2,18-dione
5H-5a,8-Methano-11H-cyclohepta[c]furo[3,4-e][1]benzopyran-5,6(7H)-dione, decahydro-13-hydroxy-1,1-dimethyl-7-methylene-, (3aS,5aS,8R,10aS,10bS,13R,13aR)- |
| Description | (-)-Isodocarpin (Isodocarpin), a diterpenoid, is a potent melanogenesis inhibitor with an IC50 of 0.19 μM in B16 4A5 cells. (-)-Isodocarpin inhibits the expression of tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 568.7±50.0 °C at 760 mmHg |
| Melting Point | 270-273℃ |
| Molecular Formula | C20H26O5 |
| Molecular Weight | 346.417 |
| Flash Point | 205.0±23.6 °C |
| Exact Mass | 346.178009 |
| PSA | 72.83000 |
| LogP | 0.94 |
| Vapour Pressure | 0.0±3.5 mmHg at 25°C |
| Index of Refraction | 1.584 |
| Hazard Codes | Xi |
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