Name | N-ethylmaleimide |
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Synonyms |
N-ethylmaleimide
EINECS 204-892-4 1H-Pyrrole-2,5-dione, 1-ethyl- n-ethyl-maleimid MFCD00005509 1-ethylmaleimide N-ethyl-maleimide N-ethylmaleic imide ethvlmaleimide n-ethvlmaleimide 1-Ethyl-1H-pyrrole-2,5-dione N-Ethylmaleinimid Ethylmaleimide |
Description | N-Ethylmaleimide (NEM) is a cysteine protease inhibitor[1]. N-ethylmaleimide specific inhibits phosphate transport in mitochondria[2]. |
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Related Catalog | |
Target |
Cysteine protease[1] |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 210.0±9.0 °C at 760 mmHg |
Melting Point | 43-46 °C(lit.) |
Molecular Formula | C6H7NO2 |
Molecular Weight | 125.13 |
Flash Point | 73.3±0.0 °C |
Exact Mass | 125.047676 |
PSA | 37.38000 |
LogP | 0.68 |
Vapour Pressure | 0.2±0.4 mmHg at 25°C |
Index of Refraction | 1.514 |
Storage condition | 2-8°C |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. Refrigerate. |
Water Solubility | 1 g/L (20 ºC) |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
Symbol |
GHS05, GHS06 |
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Signal Word | Danger |
Hazard Statements | H300-H311-H314-H317 |
Precautionary Statements | P264-P280-P301 + P310-P305 + P351 + P338-P310 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
Hazard Codes | T+:Verytoxic; |
Risk Phrases | R20/21;R28;R34;R43 |
Safety Phrases | S26-S28-S36/37/39-S45-S28A |
RIDADR | UN 2928 6.1/PG 2 |
WGK Germany | 3 |
RTECS | UX9625000 |
Packaging Group | II |
Hazard Class | 6.1 |
HS Code | 2925190090 |
~% 128-53-0 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 15 p. 4577 - 4580 |
~% 128-53-0 |
Literature: Gazzetta Chimica Italiana, , vol. 26 I, p. 438 Gazzetta Chimica Italiana, , vol. 18, p. 471,478 Gazzetta Chimica Italiana, , vol. 18, p. 476 |
~% 128-53-0 |
Literature: Organic and Biomolecular Chemistry, , vol. 10, # 14 p. 2787 - 2792,6 |
~% 128-53-0 |
Literature: Journal of Enzyme Inhibition and Medicinal Chemistry, , vol. 27, # 1 p. 117 - 124 |
Precursor 4 | |
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DownStream 7 | |
HS Code | 2925190090 |
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Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |