5995-86-8
5995-86-8 structure
- Name: Gallic acid hydrate
- Chemical Name: Gallic acid monohydrate
- CAS Number: 5995-86-8
- Molecular Formula: C7H8O6
- Molecular Weight: 188.135
- Catalog: API Other chemicals Health and epidemic prevention drugs
- Create Date: 2018-03-14 08:00:00
- Modify Date: 2026-07-04 10:44:08
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Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2)[1]. Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities[2].
| Name | Gallic acid monohydrate |
|---|---|
| Synonyms |
TIMTEC-BB SBB008781
GALLIC ACID-1-HYDRATE EXTRA 3,4,5-Trihydroxybenzoic acid hydrate GALLIC ACID MONOHYDRATE Gallic Acid Standd, 1500ppm GALLICACID,CRYSTAL ic acid monohydrate 3,4,5-Trihydroxybenzoic acid monohydrate min Gallic Acid Standd, 750ppm Benzoic acid, 3,4,5-trihydroxy-, hydrate (1:1) BETZ 0276 GALLIC ACID 1H2O 3,4,5-Trihydroxybenzoic acid monohydrate Gallic Acid , ExiPlus, Multi-Compendial GALLIC ACID, MONOHYDRATE GALLIC ACID, MONOHYDRATE LOW METALS ADE GALLIC ACID, MONOHYDRATE, GALLIC ACID, MONOHYDRATE, GALLIC ACID, MONOHYDRATE, GALLIC ACID, MONOHYDRATE Gallic Acid Extrapure RECHEM AL BE 0747 GALLIC ACID, MONOHYDRATE, LOW METALS ADEGALLIC ACID, MONOHYDRATE, LOW METALS ADEGALLIC ACID, MONOHYDRATE, LOW METALS ADEGALLIC ACID, MONOHYDRATE, LOW METALS ADE Benzoic acid, 3,4,5-trihydroxy-, monohydrate Gallic acid monohydrate Vetec(TM) ade GALLIC ACID-1-HYDRATE high qualtiy Gallic Acid Monohydrate GALLIC ACID Extra Gallic acid monohydrate, c.p 3,4,5-TRIOXYBENZOIC ACID Benzoic acid,3,4,5-trihydroxy-, hydrate (1:1) GallicAcidHydrate> RECHEM AL BE 0070 GALLIC ACID MONOHYDRATE A.C.S. RE AGENT ELECTRONIC ADE GALLIC ACID GALLIC ACID 3,4,5-Trihydroxybenzoic acid hydrate (1:1) Gallic Acid 1 Hydrate HIGH PURITY GALLIC ACID Gallic acid monohydrate , >= Gallic acid monohydrate //BP Gallic acid monohydrate >= (HPLC) MFCD00002510 Gallic Acid, Monohydrate, Crystal GALLIC ACID MONOHYDRATE & GALLIC ACID, HYDRATE GALLICACID,PURIFIED 3,4,5-trihydroxybenzoic acid,hydrate EINECS 205-749-9 |
| Description | Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2)[1]. Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities[2]. |
|---|---|
| Related Catalog | |
| Target |
COX-2 Human Endogenous Metabolite |
| In Vitro | Gallic acid is an antioxidant which can inhibit both COX-2[1]. After 18 h treatment with Gallic acid, the number of viable neutrophils is dramatically decreased from 40.3% to 27.7%, highly comparable with 26.4% for untreated neutrophils. Gallic acid fails to attenuate isoproterenol-induced myocytolysis[3]. |
| In Vivo | The food intake (2.6±0.08 g/day, p=0.69) and the body weight (2.5±0.69 g, p=0.76) of the Gallic acid group do not differ significantly from those of the control group (food intake; 2.41±0.14 g/day and the body weight; 2.83±0.84 g/day). The blood glucose tolerance in the Gallic acid group is significantly improved after 2 weeks of treatment. The blood glucose tolerance of the Gallic acid group after a treatment period of 2 weeks is also significantly better than that of the control group at 90 and 120 min ( p<0.05). The serum triglyceride concentration in the Gallic acid group (0.67±0.03 mM, p<0.05) is significantly reduced relative to that of the control group (1.08±0.20 mM). The total cholesterol concentration is similar in the control (3.19±0.27 mM) and Gallic acid (3.01±0.18 mM) groups[2]. |
| References |
| Density | 1.694 |
|---|---|
| Boiling Point | 596.6ºC at 760 mmHg |
| Melting Point | 252 °C (dec.)(lit.) |
| Molecular Formula | C7H8O6 |
| Molecular Weight | 188.135 |
| Flash Point | 250 °C |
| Exact Mass | 188.032089 |
| PSA | 107.22000 |
| LogP | 0.43730 |
| Water Solubility | 15 g/l (20 ºC) |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | LW7525000 |
| HS Code | 2918290000 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
| HS Code | 2918290000 |
|---|---|
| Summary | HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0% |