Name | 1,3,5-Tri-O-benzoyl-D-ribofuranose |
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Synonyms |
α-D-Ribofuranose, 1,3,5-tribenzoate
1,3,5-Tri-O-benzoyl-a-D-ribofuranose MFCD00080818 1,3,5-Tri-O-benzoyl-α-d-ribofuranose a-D-Ribofuranose,1,3,5-tribenzoate 1,3,5-TRIBENZOYL-A-D-RIBOFURANOSE 1,3,5-tribenzoate-a-D-Ribofuranose |
Description | 1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 629.6±55.0 °C at 760 mmHg |
Melting Point | 125-129 °C(lit.) |
Molecular Formula | C26H22O8 |
Molecular Weight | 462.45 |
Flash Point | 213.0±25.0 °C |
Exact Mass | 462.131470 |
PSA | 108.36000 |
LogP | 6.12 |
Vapour Pressure | 0.0±1.9 mmHg at 25°C |
Index of Refraction | 1.633 |
Storage condition | 2~8 ℃ |
1,3,5-Tri-O-benzoyl-α-D-ribofuranose
Revision number: 5
SAFETY DATA SHEET Section1. IDENTIFICATION Product name:1,3,5-Tri-O-benzoyl-α-D-ribofuranose
Revision number:5
Section2. HAZARDS IDENTIFICATION GHS classification PHYSICAL HAZARDSNot classified HEALTH HAZARDSNot classified ENVIRONMENTAL HAZARDSNot classified GHS label elements, including precautionary statements Pictograms or hazard symbolsNone Signal wordNo signal word Hazard statementsNone Precautionary statements:None Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substance Substance/mixture: Components:1,3,5-Tri-O-benzoyl-α-D-ribofuranose Percent:>97.0%(LC) CAS Number:22224-41-5 Chemical Formula:C26H22O8 Section4. FIRST AID MEASURES Remove victim to fresh air and keep at rest in a position comfortable for breathing. Inhalation: Get medical advice/attention if you feel unwell. Remove/Take off immediately all contaminated clothing. Rinse skin with Skin contact: water/shower. If skin irritation or rash occurs: Get medical advice/attention. Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth. Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air- tight goggles. Section5. FIRE-FIGHTING MEASURES Suitable extinguishingDry chemical, foam, water spray, carbon dioxide. media: Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so. 1,3,5-Tri-O-benzoyl-α-D-ribofuranose Section5. FIRE-FIGHTING MEASURES When extinguishing fire, be sure to wear personal protective equipment. Special protective equipment for firefighters: Section6. ACCIDENTAL RELEASE MEASURES Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak. protective equipment and Entry to non-involved personnel should be controlled around the leakage area by emergency procedures: roping off, etc. Environmental precautions: Prevent product from entering drains. Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it. containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with up: appropriate laws and regulations. Section7. HANDLING AND STORAGE Precautions for safe handling Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment. Prevent dispersion of dust. Wash hands and face thoroughly after handling. Use a local exhaust if dust or aerosol will be generated. Advice on safe handling: Avoid contact with skin, eyes and clothing. Conditions for safe storage, including any incompatibilities Storage conditions:Keep container tightly closed. Store in a refrigerator. Store away from incompatible materials such as oxidizing agents. Heat-sensitive Comply with laws. Packaging material: Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Engineering controls:Install a closed system or local exhaust as possible so that workers should not be exposed directly. Also install safety shower and eye bath. Personal protective equipment Respiratory protection: Dust respirator. Follow local and national regulations. Hand protection:Protective gloves. Eye protection:Safety glasses. A face-shield, if the situation requires. Skin and body protection: Protective clothing. Protective boots, if the situation requires. Section9. PHYSICAL AND CHEMICAL PROPERTIES Physical state (20°C):Solid Form:Crystal- Powder Colour:White - Very pale yellow Odour:No data available pH: No data available Melting point/freezing point:140°C Boiling point/range:No data available Flash point:No data available Flammability or explosive limits: Lower:No data available Upper:No data available Relative density:No data available Solubility(ies): [Water]No data available [Other solvents]No data available Section10. STABILITY AND REACTIVITY Stable under proper conditions. Chemical stability: Possibility of hazardous No special reactivity has been reported. reactions: 1,3,5-Tri-O-benzoyl-α-D-ribofuranose Section10. STABILITY AND REACTIVITY Incompatible materials: Oxidizing agents Hazardous decomposition Carbon monoxide, Carbon dioxide products: Section11. TOXICOLOGICAL INFORMATION Acute Toxicity:No data available Skin corrosion/irritation: No data available Serious eyeNo data available damage/irritation: Germ cell mutagenicity: No data available Carcinogenicity: IARC =No data available NTP =No data available Reproductive toxicity:No data available Section12. ECOLOGICAL INFORMATION Ecotoxicity: No data available Fish: Crustacea:No data available No data available Algae: Persistence / degradability: No data available No data available Bioaccumulative potential(BCF): Mobility in soil Log Pow:No data available No data available Soil adsorption (Koc): Henry's LawNo data available constant(PaM3/mol): Section13. DISPOSAL CONSIDERATIONS Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section14. TRANSPORT INFORMATION Hazards Class:Does not correspond to the classification standard of the United Nations Not listed UN-No: Section15. REGULATORY INFORMATION Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002 and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed. 1,3,5-Tri-O-benzoyl-α-D-ribofuranose SECTION 16 - ADDITIONAL INFORMATION N/A |
Hazard Codes | Xi |
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Safety Phrases | S22-S24/25 |
WGK Germany | 3 |