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17954-98-2

17954-98-2 structure

17954-98-2 structure

Name: 22-alpha-Hydroxy Cholesterol
Chemical Name: (22R)-22-hydroxycholesterol
CAS Number: 17954-98-2
Molecular Formula: C₂₇H₄₆O₂
Molecular Weight: 402.65
Catalog: Signaling Pathways Metabolic Enzyme/Protease LXR
Create Date: 2018-07-22 20:07:40
Modify Date: 2026-07-16 19:31:29
22(R)-Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22(R)-Hydroxycholesterol (Narthesterol) can be used for tangier disease research[1].

Name	(22R)-22-hydroxycholesterol
Synonyms	Cholest-5-ene-3,22-diol, (3β,22R) (20S,22R)-Cholest-5-ene-3β,22-diol 3BETA,22BETA-DIHYDROXY-5-CHOLESTENE 5-Cholestene-3β,22(R)-diol 22α-Hydroxy Cholesterol 22(R)-HYDROXYCHOLESTEROL Nthesterol 22α-Hydroxycholesterol, 5-Cholestene-3β,22(R)-diol, 5-Cholestene-3β,22[R]-diol 22BF-HYDROXYCHOLESTEROL (3β,22R)-Cholest-5-ene-3,22-diol 22(R)-Hydroxycholestero 22-ALPHA-HYDROXYCHOLESTEROL 22[R]-Hydroxycholesterol (not deuterated) (22R)-Cholest-5-ene-3β,22-diol 5-Cholestene-3β,22[R]-diol 5-CHOLESTEN-3-BETA, 22(R)-DIOL Chlorambucil Impurity 8 Narthesterol (3beta,22R)-Cholest-5-ene-3,22-diol 22α-hydroxycholesterol Cholest-5-ene-3β,22(R)-diol CHOLEST-5-ENE-3BETA,22R-DIOL Cholest-5-ene-3,22-diol, (3beta,22R) 5-CHOLESTEN-3β, 22(R)-DIOL (3β,22S)-Cholest-5-ene-3,22-diol 22BETA-HYDROXYCHOLESTEROL 22-HYDROXYCHOLESTEROL (22R) (22a-Hydroxycholesterol, 5-Cholestene-322(R)-diol) 22R-OHC 22(R)-OH-CH Cholesterol 22α-Hydroxy 5-CHOLESTENE-3BETA,22[R]-DIOL 22(S)-hydroxycholesterol

Description	22(R)-Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22(R)-Hydroxycholesterol (Narthesterol) can be used for tangier disease research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> LXR Research Areas >> Metabolic Disease
References	[1]. Costet P, et al. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J Biol Chem. 2000 Sep 8;275(36):28240-5.

Density	1.0±0.1 g/cm3
Boiling Point	513.1±23.0 °C at 760 mmHg
Molecular Formula	C₂₇H₄₆O₂
Molecular Weight	402.65
Flash Point	213.5±17.2 °C
Exact Mass	402.349792
PSA	40.46000
LogP	7.66
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.536

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Precursor 0
DownStream 2
19243-30-2 481-21-0

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