22-alpha-Hydroxy Cholesterol

Modify Date: 2025-08-25 11:45:56

22-alpha-Hydroxy Cholesterol structure	Common Name	22-alpha-Hydroxy Cholesterol
	CAS Number	17954-98-2	Molecular Weight	402.65
	Density	1.0±0.1 g/cm3	Boiling Point	513.1±23.0 °C at 760 mmHg
	Molecular Formula	C₂₇H₄₆O₂	Melting Point	N/A
	MSDS	USA	Flash Point	213.5±17.2 °C

Use of 22-alpha-Hydroxy Cholesterol

22(R)-Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22(R)-Hydroxycholesterol (Narthesterol) can be used for tangier disease research[1].

Name	(22R)-22-hydroxycholesterol
Synonym	More Synonyms

Description	22(R)-Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22(R)-Hydroxycholesterol (Narthesterol) can be used for tangier disease research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> LXR Research Areas >> Metabolic Disease
References	[1]. Costet P, et al. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J Biol Chem. 2000 Sep 8;275(36):28240-5.

Density	1.0±0.1 g/cm3
Boiling Point	513.1±23.0 °C at 760 mmHg
Molecular Formula	C₂₇H₄₆O₂
Molecular Weight	402.65
Flash Point	213.5±17.2 °C
Exact Mass	402.349792
PSA	40.46000
LogP	7.66
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.536

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Precursor 0
DownStream 2
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Narthesterol

22BF-HYDROXYCHOLESTEROL

22(S)-hydroxycholesterol

(3β,22S)-Cholest-5-ene-3,22-diol

22BETA-HYDROXYCHOLESTEROL

Cholest-5-ene-3,22-diol, (3β,22S)-

22R-OHC

22(R)-HYDROXYCHOLESTEROL