157327-96-3

157327-96-3 structure

Name: 3’-dC(Bz)-2’-phosphor amidite
Chemical Name: 3'-dc cep
CAS Number: 157327-96-3
Molecular Formula: C₄₆H₅₂N₅O₈P
Molecular Weight: 833.91
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-09-24 23:40:23
Modify Date: 2024-01-09 11:59:08
3’-dC(Bz)-2’-phosphor amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	3'-dc cep
Synonyms	Midostaurin 4'-N-benzoyl staurosprine Benzoylstaurosporine Cgp 41 251 4'-N-benzoylstaurosporine

Description	3’-dC(Bz)-2’-phosphor amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.