157327-96-3

157327-96-3 structure
157327-96-3 structure
  • Name: 3’-dC(Bz)-2’-phosphor amidite
  • Chemical Name: 3'-dc cep
  • CAS Number: 157327-96-3
  • Molecular Formula: C46H52N5O8P
  • Molecular Weight: 833.91
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-09-24 23:40:23
  • Modify Date: 2024-01-09 11:59:08
  • 3’-dC(Bz)-2’-phosphor amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 3'-dc cep
Synonyms Midostaurin
4'-N-benzoyl staurosprine
Benzoylstaurosporine
Cgp 41 251
4'-N-benzoylstaurosporine
Description 3’-dC(Bz)-2’-phosphor amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Molecular Formula C46H52N5O8P
Molecular Weight 833.91
Exact Mass 833.35500
PSA 159.99000
LogP 8.54318