1197-09-7

1197-09-7 structure

Name: 1-(3,4-Dihydroxyphenyl)ethanone
Chemical Name: 3',4'-dihydroxyacetophenone
CAS Number: 1197-09-7
Molecular Formula: C₈H₈O₃
Molecular Weight: 152.147
Catalog: Natural product Phenols
Create Date: 2018-08-24 09:33:45
Modify Date: 2024-01-02 16:17:10
3',4'-Dihydroxyacetophenone (3,4-DHAP), isolated from Picea Schrenkiana Needles exhibits a strong suppressive action against tyrosinase activity, with an IC50 of 10 μM. 3',4'-Dihydroxyacetophenone (3,4-DHAP) is a vasoactive agent and antioxidant[1][2].

Name	3',4'-dihydroxyacetophenone
Synonyms	3,4-Dihydroxyacetophenone 4-Acetocatechol 4-Acetylpyrocatechol 3',4'-Dihydroxyacetophenone MFCD00016439 1-(3,4-Dihydroxyphenyl)ethanone Ethanone, 1-(3,4-dihydroxyphenyl)-

Description	3',4'-Dihydroxyacetophenone (3,4-DHAP), isolated from Picea Schrenkiana Needles exhibits a strong suppressive action against tyrosinase activity, with an IC50 of 10 μM. 3',4'-Dihydroxyacetophenone (3,4-DHAP) is a vasoactive agent and antioxidant[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase
Target	IC50: 10 μM (Tyrosinase)[1].
References	[1]. You Jung Kim, et al. Antimelanogenic Activity of 3,4-dihydroxyacetophenone: Inhibition of Tyrosinase and MITF. Biosci Biotechnol Biochem. 2006 Feb;70(2):532-4. [2]. Xiao Ruan, et al. Autotoxicity and Allelopathy of 3,4-dihydroxyacetophenone Isolated From Picea Schrenkiana Needles. Molecules. 2011 Oct 24;16(10):8874-93.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11- 1980- Volume(issue)/page/year: 11,358,1980

HS Code	2914501900
Summary	2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%