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89796-99-6

89796-99-6 structure
89796-99-6 structure
  • Name: Aceclofenac
  • Chemical Name: aceclofenac
  • CAS Number: 89796-99-6
  • Molecular Formula: C16H13Cl2NO4
  • Molecular Weight: 354.185
  • Catalog: API Antipyretic analgesics Non-steroidal anti-inflammatory drugs
  • Create Date: 2018-06-10 17:13:09
  • Modify Date: 2026-07-01 12:27:53
  • Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.Target: COXAceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Aceclofenac has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Aceclofenac is the glycolic acid ester of diclofenac [1].
Name aceclofenac
Synonyms 2-((2,6-dichlorophenyl)amino)benzeneaceticacidcboxymethylester
AceclofenacDMF API
ACECLOFENAC, IMP. C : ETHYL 2-[2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL]ACETATE (ETHYL ESTER OF DICLOFENAC) MM(CRM STANDD)
2-[2-[2-(2,6-dichlorophenyl)aminophenyl]acetyl]oxyacetic acid
2-((2,6-dichlorophenyl)amino)-benzeneaceticacicboxymethylester
2-(2-(2-((2,6-dichlorophenyl)amino)phenyl)acetoxy)acetic acid
Aceclofar
Preservex
2-(39-Chlorobenzoyl)benzoic&acid
Falcol
Aceclofenac //BP
Glycolic Acid [o-(2,6-Dichloroanilino)phenyl]acetate Ester
Aceclofenac D4Q: What is Aceclofenac D4 Q: What is the CAS Number of Aceclofenac D4 Q: What is the storage condition of Aceclofenac D4 Q: What e the applications of Aceclofenac D4
Aceclofenac for peak identification (Y0001094)
ACECLOFENAC-D2
Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, cboxymethyl ester
ACECLOFENAC
Aceclofenac for peak identification CRS
[[[2-[(2,6-Dichlorophenyl)amino]phenyl]acetyl]oxy]acetic acid
ACECLOFENAC, IMP. E : ETHYL 2-[(2-{2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL}ACETYL)OXY]ACETATE (ETHYL ESTER OF ACECLOFENAC) MM(CRM STANDD)
ACECLOFENAC IP
ACECLOFENAC, IMPURITY H[[[[[[[2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL]ACETYL]OXY]ACETYL]OXY] ACETYL]OXY] ACETIC ACID STANDD
MFCD00864296
Biofenac
ACECLOFENAC, IMP. F : BENZYL 2-[(2-{2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL}ACETYL)OXY]ACETATE(BENZYL ESTER OF ACECLOFENAC) MM(CRM STANDD)
Zerodol
PR-82/3
Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, carboxymethyl ester
Aceclofenac iMpurity
Gerbin
ACECLOFENAC, IMP. IMP. G :2[[2-[[2-[2-[(2,6-DICHLORPHENYL)-AMINO]PHENYL]ACETYL]OXY]ACETYL]OXY]ACETIC ACID (ACETIC ACECLOFENAC) MM(CRM STANDD)
Acelofenac
Aceclof
ACECLOFENAC, IMP. D : METHYL 2-[(2-{2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL}ACETYL)OXY]ACETATE (METHYL ESTER OF ACECLOFENAC) MM(CRM STANDD)
Preservex|||Airtal
ACECLOFENAC, IMP. A : 2-{2-[(2,6-DICHLOROPHENYL)AMINO]-PHENYL}ACETIC ACID (DICLOFENAC) MM(CRM STANDD)
Aceclofenac IP/BP
Aceclofenac /BP)
ACECLOFENAC, IMP. C : ETHYL 2-[2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL]ACETATE (ETHYL ESTER OF DICLOF
Aceclofenac NSAID. Cyclooxygenase inhibitor
Tresquim
[[[[[[[2-[(2,6-Dichlorophenyl)amino
ACECLOFENAC, IMP. I :1-(2,6-DICHLOROPHENYL)INDOLIN-2-ONE MM(CRM STANDD)
2-[(2，6-Dichlorophenyl)amino]phenylacetoxyacetic acid
Airtal
Aceclofenac-D4
Aceclofenacr
sopropyl [2-[(2,6-Dichlorophenyl)amino]phenyl]acetate(Isopropyl Ester of Diclofenac)
o-(2,6-Dichloranilino)-phenyl-acetoxy-essigsure
Aceclofenac >
AceclofenacQ: What is Aceclofenac Q: What is the CAS Number of Aceclofenac Q: What is the storage condition of Aceclofenac Q: What e the applications of Aceclofenac
Aceclofenac D7Q: What is Aceclofenac D7 Q: What is the CAS Number of Aceclofenac D7
EINECS 205-783-4
2-[2-(2,6-Dichloroanilino)phenylacetoxy]acetic Acid
ACECLOFENAC REFERENCE SPECTRUM Y(CRM STANDD)
ACECLOFENAC, IMPURITY FBENZYL[[[2-[(2,6-DICHLOROPHENYL)AMINO] PHENYL]ACETYL]OXY]ACETATE STANDD
(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}acetoxy)acetic acid
B.N-[3-acetyl-4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide(diacetolol)
Aceclofenac in methanol
ACECLOFENAC, IMP. B : METHYL 2-{2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL}ACETATE(METHYL ESTER OF DICLOFENAC) MM(CRM STANDD)
[[2-[2-[(2,6-Dichlorophenyl)amino]phenyl]-1-oxoethyl]oxy]acetic acid
ACECLOFENAC, MM(CRM STANDD)
Description Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.Target: COXAceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Aceclofenac has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Aceclofenac is the glycolic acid ester of diclofenac [1].
Related Catalog
Target

COX-2:3 μM (IC50)

COX-1:7.3 μM (IC50)

References

[1]. Dannhardt G, et al. In-vitro test system for the evaluation of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors based on a single HPLC run with UV detection using bovine aortic coronary endothelial cells (BAECs). Inflamm Res. 2001 May;50(5):262-9.
Density 1.5±0.1 g/cm3
Boiling Point 486.0±45.0 °C at 760 mmHg
Melting Point 149-153°C
Molecular Formula C16H13Cl2NO4
Molecular Weight 354.185
Flash Point 247.8±28.7 °C
Exact Mass 353.022156
PSA 75.63000
LogP 4.16
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.639
Storage condition -20°C Freezer

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CY1577900
CHEMICAL NAME :
Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)-, carboxymethyl ester
CAS REGISTRY NUMBER :
89796-99-6
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H13-Cl2-N-O4
MOLECULAR WEIGHT :
354.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
130 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 41,1265,1991
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H319-H410
Precautionary Statements P273-P301 + P310-P305 + P351 + P338-P501
Hazard Codes Xi
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases S26-S36
RIDADR 2811.0
WGK Germany 3
Hazard Class 6.1
HS Code 2922509090
139272-68-7 structure

139272-68-7

~56%

89796-99-6 structure

89796-99-6

Literature: US2004/24057 A1, ; Page/Page column 53 ;
15307-79-6 structure

15307-79-6

~%

89796-99-6 structure

89796-99-6

Literature: Journal of Crystallographic and Spectroscopic Research, , vol. 22, # 3 p. 323 - 328
100499-89-6 structure

100499-89-6

~%

89796-99-6 structure

89796-99-6

Literature: Journal of Crystallographic and Spectroscopic Research, , vol. 22, # 3 p. 323 - 328
HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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