99519-84-3

99519-84-3 structure

Name: L-651,582
Chemical Name: 5-amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]triazole-4-carboxamide
CAS Number: 99519-84-3
Molecular Formula: C₁₇H₁₂Cl₃N₅O₂
Molecular Weight: 424.67
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2018-10-12 10:10:41
Modify Date: 2026-07-01 08:48:09
Carboxyamidotriazole (L 651582; CAI) is a blocker of non-voltage dependent calcium channel[1]. Carboxyamidotriazole (L 651582; CAI) is a non-cytotoxic anti-tumor drug, which also shows anti-inflammatory activity[2].

Name	5-amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]triazole-4-carboxamide
Synonyms	4-CAI Cboxyamidotriazole >= (HPLC) 5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-cboxamide L-651582 cboxyaMido-triazole(5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-cboxaMide) CAI Carboxyamido-triazole 1-[3,5-Dichloro-4-(4-chlorobenzoyl)benzyl]-5-amino-1H-1,2,3-triazole-4-cboxamide 5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-cboxamide, Cboxyamidotriazole Merck L651582 5-amino-1-[3,5-dichloro-4-(4-chloro-benzoyl)-benzyl]-1H-[1,2,3]triazole-4-cboxylic acid aMide 5-Amino-1-[3,5-dichloro-4-(4-chlorobenzoyl)benzyl]-1H-[1,2,3]triazole-4-cboxylic acid amide 1H-1,2,3-TRIAZOLE-4-CBOXAMIDE-5-AMINO-1-[[3,5-DICHLORO-4-(4-CHLOROBENZOYL)PHENYL]METHYL] cboxyamido-triazole 5-AMINO-1-[[3,5-DICHLORO-4-(4-CHLORO-BENZOYL)-PHENYL]METHYL]-1H-1,2,3-TRIAZOLE-4-CBOXAMIDE 5-Amino-1-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1H-1,2,3-triazole-4-cboxamide Carboxyamidotriazole 5-amino-1-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1,2,3-triazole-4-cboxamide MERCK L651582

Description	Carboxyamidotriazole (L 651582; CAI) is a blocker of non-voltage dependent calcium channel[1]. Carboxyamidotriazole (L 651582; CAI) is a non-cytotoxic anti-tumor drug, which also shows anti-inflammatory activity[2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	Calcium channel[1]
References	[1]. Chen C, et al. Carboxyamidotriazole Synergizes with Sorafenib to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis. J Pharmacol Exp Ther. 2017 Aug;362(2):219-229. [2]. Hussain MM, et al. J Clin Oncol. 2003 Dec 1;21(23):4356-63.