Shanghai Nianxing Industrial Co., Ltd
China
Product Name: coenzymeB12
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Cobamamide
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: cobamamide
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

13870-90-1

13870-90-1 structure

13870-90-1 structure

Name: coenzyme B12
Chemical Name: cobamamide
CAS Number: 13870-90-1
Molecular Formula: C₇₂H₉₉CoN₁₈O₁₇P
Molecular Weight: 1579.582
Catalog: API Vitamins and minerals Vitamin B drugs
Create Date: 2018-02-16 08:00:00
Modify Date: 2024-01-02 17:03:18
Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase[1]

Name	cobamamide
Synonyms	5'-Deoxyadenosylcobalamin a-(5,6-Dimethylbenzimidazolyl)-Co-5'-deoxyadenosylcobamide DBC 5,6-Dimethylbenzimidazolyl-Co-5'-deoxyadenosylcobamide Coenzyme B12 Dibenzcozamide Coenzyme B12 DBC coenzyme Adenosyl cobalamine Indusil T α-(5,6-Dimethylbenzimidazolyl)cobamide coenzyme Vitamin B12 coenzyme 5,6-Dimethylbenzimidazolylcobamide 5'-Deoxyadenosine Dimebenzcozamide Adenosyl-B12 Calomide AdoCbl DBC (VAN) Cobamamide Cobalamine coenzyme Deoxyadenosylcobalamin 5'-Deoxyadenosylcobalamine Cobalamin coenzyme a-(5,6-Dimethylbenzimidazolyl)cobamide coenzyme Co-(5'-Deoxy-5'-adenosyl)-a-(5,6-dimethyl-1H-benzimidazolyl)cobamide 5'-Deoxyadenosyl Vtamin B12 Funacomide Dibencozide Desoxyadenosylcobalamine

Description	Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase[1]
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Adenosylcobalamin serves as the cofactor for a group of enzymes that catalyze unusual rearrangement or elimination reactions[1].
References	[1]. Kumudha A, et al. Characterization of vitamin B12 in Dunaliella salina. J Food Sci Technol. 2016 Jan;53(1):888-94. [2]. Marsh EN, et al. Adenosylcobalamin enzymes: Theory and experiment begin to converge. Biochim Biophys Acta. 2012 Nov;1824(11):1154-64.

Molecular Formula	C₇₂H₉₉CoN₁₈O₁₇P
Molecular Weight	1579.582
Exact Mass	1578.658325
PSA	583.18000
LogP	6.19200
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GG3800000

CHEMICAL NAME :: Cobinamide, O-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole

CAS REGISTRY NUMBER :: 13870-90-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C72-H100-Co-N18-O17-P

MOLECULAR WEIGHT :: 1579.80

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,405,1990

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GG3800000
HS Code	2936260000

HS Code	2936260000

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