477775-73-8

477775-73-8 structure
477775-73-8 structure
  • Name: Benzyl-PEG8-alcohol
  • Chemical Name: 2-[2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • CAS Number: 477775-73-8
  • Molecular Formula: C23H40O9
  • Molecular Weight: 460.55800
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-06-01 06:59:00
  • Modify Date: 2024-01-11 17:33:45
  • Benzyl-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-[2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms 1-phenyl-2,5,8,11,14,17,20,23-octaoxapenta-cosan-25-ol
octaethylene glycol monobenzyl ether
Description Benzyl-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C23H40O9
Molecular Weight 460.55800
Exact Mass 460.26700
PSA 94.07000
LogP 1.31170