89346-82-7

89346-82-7 structure

Name: Tosylate of Tetraethylene glycol monobenzyl ether
Chemical Name: 4-methylbenzenesulfonic acid,2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethanol
CAS Number: 89346-82-7
Molecular Formula: C₂₂H₃₂O₈S
Molecular Weight: 456.55000
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-06-22 04:12:06
Modify Date: 2025-08-26 07:15:51
Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name	4-methylbenzenesulfonic acid,2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethanol
Synonyms	tetraethylene glycol monobenzyl ether tosylate 13-phenyl-3,6,9,12-tetraoxatridecan-1-yl p-toluenesulfonate 2,5,8,11-Tetraoxatridecan-13-ol,1-phenyl-,4-methylbenzenesulfonate 1-phenyl-2,5,8,11-tetraoxatridecan-13-yl 4-methylbenzenesulfonate Tosylate of Tetraethylene glycol monobenzyl ether

Description	Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Hazard Codes	Xi

86259-87-2

98-59-9

~10%

89346-82-7

Literature: WISCONSIN ALUMNI RESEARCH FOUNDATION Patent: WO2008/70490 A2, 2008 ; Location in patent: Page/Page column 33 ;

100-39-0

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Literature: Jain, Ahamindra; Huang, Shaw G.; Whitesides, George M. Journal of the American Chemical Society, 1994 , vol. 116, # 12 p. 5057 - 5062

112-60-7

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Literature: Ahmed, Saleh A.; Tanaka, Mutsuo Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9884 - 9886

100-44-7

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