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  • DC Chemicals Limited
  • China
  • Product Name: ADT-OH
  • Price: $500.0/100mg $900.0/250mg $1800.0/1g $1400.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

18274-81-2

18274-81-2 structure
18274-81-2 structure
  • Name: Desmethylanethol trithione
  • Chemical Name: 4-(5-sulfanyldithiol-3-ylidene)cyclohexa-2,5-dien-1-one
  • CAS Number: 18274-81-2
  • Molecular Formula: C9H6OS3
  • Molecular Weight: 226.33800
  • Create Date: 2018-11-26 10:35:22
  • Modify Date: 2024-01-03 12:28:14
  • ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. ADT-OH has the potential for the research of cancer diseases[1].

Name 4-(5-sulfanyldithiol-3-ylidene)cyclohexa-2,5-dien-1-one
Synonyms Desmethylanethol trithione
Desmethylanethol dithiolthione
desmethyl anethole trithione
4-Hydroxyanethole trithione
Desmethyl-adt
5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione
Description ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. ADT-OH has the potential for the research of cancer diseases[1].
Related Catalog
References

[1]. Cai F, et al. ADT-OH, a hydrogen sulfide-releasing donor, induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. Cell Death Dis. 2020;11(1):33.

Density 1.48g/cm3
Boiling Point 322.2ºC at 760mmHg
Melting Point 191-192 ºC
Molecular Formula C9H6OS3
Molecular Weight 226.33800
Flash Point 148.6ºC
Exact Mass 225.95800
PSA 106.47000
LogP 3.10180
Vapour Pressure 0.000284mmHg at 25°C
Index of Refraction 1.757
Storage condition 2-8°C
Hazard Codes Xi
HS Code 2930909090

~49%

18274-81-2 structure

18274-81-2

Literature: ANTIBE THERAPEUTICS INC.; CIRINO, Giuseppe; CALIENDO, Giuseppe; SANTAGADA, Vincenzo; FIORUCCI, Stefano Patent: WO2006/125295 A1, 2006 ; Location in patent: Page/Page column 40-41; 51 ;

~51%

18274-81-2 structure

18274-81-2

Literature: ANTIBE THERAPEUTICS INC. Patent: US2008/207564 A1, 2008 ; Location in patent: Page/Page column 11; 14-16 ;

~86%

18274-81-2 structure

18274-81-2

Literature: Guan, Mei; Fan, Wei; Qian, Shan; Xiao, Rui Qi; Wu, Yong Chinese Chemical Letters, 2010 , vol. 21, # 12 p. 1427 - 1429

~58%

18274-81-2 structure

18274-81-2

Literature: Zanatta, Shannon D.; Jarrott, Bevyn; Williams, Spencer J. Australian Journal of Chemistry, 2010 , vol. 63, # 6 p. 946 - 957

~%

18274-81-2 structure

18274-81-2

Literature: Zanatta, Shannon D.; Jarrott, Bevyn; Williams, Spencer J. Australian Journal of Chemistry, 2010 , vol. 63, # 6 p. 946 - 957

~%

18274-81-2 structure

18274-81-2

Literature: Zanatta, Shannon D.; Jarrott, Bevyn; Williams, Spencer J. Australian Journal of Chemistry, 2010 , vol. 63, # 6 p. 946 - 957

~%

18274-81-2 structure

18274-81-2

Literature: Lozac'h et al. Bulletin de la Societe Chimique de France, 1953 , p. 1016,1017, 1019

~%

18274-81-2 structure

18274-81-2

Literature: Lozac'h et al. Bulletin de la Societe Chimique de France, 1953 , p. 1016,1017, 1019
HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%