GL Biochem (Shanghai) Ltd.
China
Product Name: [D-Pro194]-IL-1 b (193-195) (human)
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: L-LYSYL-D-PROLYL-L-THREONINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Taiwan Oyi peptide Co. Ltd
China
Product Name: L-LYSYL-D-PROLYL-L-THREONINE
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Vinnie

117027-34-6

117027-34-6 structure

117027-34-6 structure

Name: L-LYSYL-D-PROLYL-L-THREONINE
Chemical Name: h-lys-d-pro-thr-oh
CAS Number: 117027-34-6
Molecular Formula: C₁₅H₂₈N₄O₅
Molecular Weight: 344.41
Create Date: 2018-12-22 20:45:11
Modify Date: 2024-01-29 12:55:53
Lys-D-Pro-Thr, an IL-1beta analogue, is a potent IL-1 inhibitor. Lys-D-Pro-Thr inhibits the protective effects of IL-1 beta[1][2].

Name	h-lys-d-pro-thr-oh
Synonyms	l-lysyl-d-prolyl-l-threonine l-lys-d-pro-l-thr lys-d-pro-thr interleukin 1b antagonist [D-Pro194]-IL-1 b (193-195) (human)

Description	Lys-D-Pro-Thr, an IL-1beta analogue, is a potent IL-1 inhibitor. Lys-D-Pro-Thr inhibits the protective effects of IL-1 beta[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Metabolic Disease
Target	IL-1
In Vivo	Lys-D-Pro-Thr (10 mg/kg; 腹腔给药; 持续 4 天) 抑制 fMLP (HY-P0224) 和 MMK-1 (HY-P1117) 对依托泊苷 (HY-13629) 诱导脱发的保护作用[1]。 Animal Model: 11-d-old rats[1] Dosage: 10 mg/kg Administration: IP; for 4 days Result: Inhibited the protective effect of fMLP and that of MMK-1 against Etoposide-induced alopecia. It alone did not induce alopecia.
References	[1]. Takahiro Tsuruki, et al. Mechanism of the protective effect of intraperitoneally administered agonists for formyl peptide receptors against chemotherapy-induced alopecia. Biosci Biotechnol Biochem. 2007 May;71(5):1198-202. [2]. Y Uehara, et al. Central administration of Lys-D-Pro-Thr, an interleukin-1 beta 193-195 analogue, stimulates feeding in rats. Neuropeptides. 1991 May;19(1):9-11.

Density	1.288g/cm3
Boiling Point	691.3ºC at 760mmHg
Molecular Formula	C₁₅H₂₈N₄O₅
Molecular Weight	344.41
Flash Point	371.9ºC
Exact Mass	344.20600
PSA	158.98000
LogP	0.11330
Vapour Pressure	4.12E-22mmHg at 25°C
Index of Refraction	1.56

Safety Phrases	22-24/25