Shanghai Nianxing Industrial Co., Ltd
China
Product Name: natsudaidain
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: natsudaidain
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

35154-55-3

35154-55-3 structure

35154-55-3 structure

Name: Natsudaidain
Chemical Name: 2-(3,4-dimethoxyphenyl)-3-hydroxy-5,6,7,8-tetramethoxychromen-4-one
CAS Number: 35154-55-3
Molecular Formula: C₂₁H₂₂O₉
Molecular Weight: 418.39
Catalog: Signaling Pathways MAPK/ERK Pathway p38 MAPK
Create Date: 2016-05-11 17:33:17
Modify Date: 2025-08-25 16:31:50
Natsudaidain is a kind of polymethoxyflavone. Natsudaidain can be isolated from Citrus plants. Natsudaidain inhibits tumor necrosis factor-α and cyclooxygenase-2 production n by suppressing p38 MAPK phosphorylation on mast cells[1].

Name	2-(3,4-dimethoxyphenyl)-3-hydroxy-5,6,7,8-tetramethoxychromen-4-one
Synonyms	3-hydroxy-5,6,7,8,3',4'-hexamethoxyflavone 3-Hydroxy-3',4',5,6,7,8-hexamethoxyflavone 3-hydroxynobiletin Natsudaidain

Description	Natsudaidain is a kind of polymethoxyflavone. Natsudaidain can be isolated from Citrus plants. Natsudaidain inhibits tumor necrosis factor-α and cyclooxygenase-2 production n by suppressing p38 MAPK phosphorylation on mast cells[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK
References	[1]. Takuya Matsui, et al. Effect of natsudaidain isolated from Citrus plants on TNF-α and cyclooxygenase-2 expression in RBL-2H3 cells. Journal of Pharmacy and Pharmacology. 2009, 61, 1.

Density	1.314g/cm3
Boiling Point	608.3ºC at 760mmHg
Molecular Formula	C₂₁H₂₂O₉
Molecular Weight	418.39
Flash Point	212.3ºC
Exact Mass	418.12600
PSA	105.82000
LogP	3.21720
Index of Refraction	1.579

Hazard Codes	Xi
HS Code	2914509090

478-01-3 structure

478-01-3

~82%

35154-55-3 structure

35154-55-3

Literature: Tetrahedron, , vol. 60, # 11 p. 2647 - 2655

10496-67-0 structure

10496-67-0

~%

35154-55-3 structure

35154-55-3

Literature: Tetrahedron, , vol. 60, # 11 p. 2647 - 2655

114021-62-4 structure

114021-62-4

~%

35154-55-3 structure

35154-55-3

Literature: Tetrahedron, , vol. 60, # 11 p. 2647 - 2655

76650-20-9 structure

76650-20-9

~%

35154-55-3 structure

35154-55-3

Literature: Tetrahedron, , vol. 60, # 11 p. 2647 - 2655

2306-27-6 structure

2306-27-6

~%

35154-55-3 structure

35154-55-3

Literature: Tetrahedron, , vol. 60, # 11 p. 2647 - 2655

21763-80-4 structure

21763-80-4

~%

35154-55-3 structure

35154-55-3

Literature: Tetrahedron, , vol. 60, # 11 p. 2647 - 2655

683278-67-3 structure

683278-67-3

~%

35154-55-3 structure

35154-55-3

Literature: Tetrahedron, , vol. 60, # 11 p. 2647 - 2655

120-14-9 structure

120-14-9

~%

35154-55-3 structure

35154-55-3

Literature: Tetrahedron, , vol. 60, # 11 p. 2647 - 2655

832-58-6 structure

832-58-6

~%

35154-55-3 structure

35154-55-3

Literature: Tetrahedron, , vol. 60, # 11 p. 2647 - 2655

Precursor 9
478-01-3 10496-67-0 114021-62-4 76650-20-9
2306-27-6 21763-80-4 683278-67-3 120-14-9
832-58-6
DownStream 1
1178-24-1

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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