5081-51-6

5081-51-6 structure

Name: Vasicinol
Chemical Name: Vasicinol
CAS Number: 5081-51-6
Molecular Formula: C₁₁H₁₂N₂O₂
Molecular Weight: 204.23
Catalog: Natural product Alkaloid
Create Date: 2017-09-01 12:25:31
Modify Date: 2024-01-10 17:20:38
Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM). Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE). Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica[1][2].

Name	Vasicinol
Synonyms	(3R)-1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazoline-3,7-diol Pyrrolo[2,1-b]quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (3S)- Pyrrolo[2,1-b]quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (3R)- Pyrrolo(2,1-b)quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (R)- (3S)-1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazoline-3,7-diol

Description	Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM). Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE). Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
References	[1]. Gao H, et al. Inhibitory effect on α-glucosidase by Adhatoda vasica Nees. Food Chem. 2008 Jun 1;108(3):965-72. [2]. Tehreem S, et al. A UPLC-DAD-Based Bio-Screening Assay for the Evaluation of the Angiotensin Converting Enzyme Inhibitory Potential of Plant Extracts and Compounds: Pyrroquinazoline Alkaloids from Adhatoda vasica as a Case Study. Molecules. 2021 Nov 18;26(22):6971.

Hazard Codes	Xi