Name | carnosic acid |
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Synonyms |
Salvin
4a(2H)-Phenanthrenecarboxylic acid, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,10aS)- Carnosic acid RoseOx 11,12-Dihydroxyabieta-8,11,13-trien-20-oic acid Carnosic acid (4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-4a-carboxylic acid MFCD02259459 Carsonic acid Carnosolic Acid |
Description | Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity. |
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Related Catalog | |
In Vitro | Carnosic acid, a phenolic diterpene, is enriched in the leaves of Lamiaceae plants, and is particularly high in dried leaves of Rosmarinus officinalis L. and Salvia officinalis. Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity. It is widely reported that Carnosic acid has a therapeutic potential in different types of cancer, mostly based on in vitro experiments. Carnosic acid has also shown neuroprotective effects in experimental models of neurodegenerative diseases, mainly through activation of the antioxidant NRF2/ARE pathway[1]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 506.4±50.0 °C at 760 mmHg |
Melting Point | 190 °C |
Molecular Formula | C20H28O4 |
Molecular Weight | 332.434 |
Flash Point | 274.2±26.6 °C |
Exact Mass | 332.198761 |
PSA | 77.76000 |
LogP | 4.93 |
Vapour Pressure | 0.0±1.4 mmHg at 25°C |
Index of Refraction | 1.576 |
Storage condition | −20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xn |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
~70% 3650-09-7 |
Literature: Tada, Masahiro; Ohkanda, Tomoyuki; Kurabe, Jun Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 1 p. 27 - 29 |
Precursor 1 | |
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DownStream 3 | |