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28608-75-5

28608-75-5 structure
28608-75-5 structure
  • Name: Orientin
  • Chemical Name: Orientine
  • CAS Number: 28608-75-5
  • Molecular Formula: C21H20O11
  • Molecular Weight: 448.377
  • Catalog: Biochemical Natural product
  • Create Date: 2018-09-23 17:58:54
  • Modify Date: 2025-08-20 21:16:59
  • Orientin is a naturally occurring bioactive flavonoid that possesses diverse biological properties, including anti-inflammation, anti-oxidative, anti-tumor, and cardio protection. Orientin is a promising neuroprotective agent suitable for therapy for neuropathic pain[1][2].

Name Orientine
Synonyms isoorientin
(1S)-1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
2-(3,4-Dihydroxyphényl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]-4H-chromén-4-one
Orientin 8-C-β-D-glucopyranoside
3',4',5,7-tetrahydroxyflavone-8-C-glucoside
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-4H-chromen-4-on
Luteolin-8-C-glucoside
3',4',5,7-tetrahydroxyflavone 8-glucoside
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-
D-Glucitol, 1,5-anhydro-1-C-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-8-yl]-, (1S)-
Orientin
lutexin
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-4H-chromen-4-one
2-(3,4-Dihydroxyphenyl)-8-b-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
Description Orientin is a naturally occurring bioactive flavonoid that possesses diverse biological properties, including anti-inflammation, anti-oxidative, anti-tumor, and cardio protection. Orientin is a promising neuroprotective agent suitable for therapy for neuropathic pain[1][2].
Related Catalog
References

[1]. Dhakal H, et al. Inhibitory effects of orientin in mast cell-mediated allergic inflammation. Pharmacol Rep. 2020 Jan 24.

[2]. Guo D, et al. Orientin and neuropathic pain in rats with spinal nerve ligation. 61Int Immunopharmacol. 2018 May;58:72-79.

Density 1.8±0.1 g/cm3
Boiling Point 816.1±65.0 °C at 760 mmHg
Melting Point 260-285ºC
Molecular Formula C21H20O11
Molecular Weight 448.377
Flash Point 289.1±27.8 °C
Exact Mass 448.100555
PSA 201.28000
LogP 1.58
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.767
Storage condition 2~8°C
Water Solubility 1 M NaOH: soluble1mg/mL, clear, yellow-orange

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ3009300
CHEMICAL NAME :
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-d ihydroxy-
CAS REGISTRY NUMBER :
28608-75-5
LAST UPDATED :
199106
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H20-O11
MOLECULAR WEIGHT :
448.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
50 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 246,205,1991
Hazard Codes Xi
Safety Phrases 24/25
RIDADR NONH for all modes of transport
RTECS DJ3009300
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