26544-34-3

26544-34-3 structure

Name: Apiin
Chemical Name: Apiin
CAS Number: 26544-34-3
Molecular Formula: C₂₆H₂₈O₁₄
Molecular Weight: 564.492
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-03-06 08:00:00
Modify Date: 2024-01-02 17:13:42
Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells[1].

Name	Apiin
Synonyms	APIIN Apioside APIGENIN-7-APIOGLUCOSIDE 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 4-O-[(3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl]-β-D-glucopyranoside apigenin-7-O-apiosyl(1->2)glucoside apigenin 7-O-apiosylglucoside 4',5,7-Trihydroxyflavone-7-apiosylglucoside 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-[[4-O-[(3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-β-D-glucopyranosyl]oxy]- 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 4-O-[(3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-β-D-glucopyranoside 7-(2-APIOSYLGLUCOSYL)APIGENIN Apigenin-7-(2-O-apiosylglucoside) 7-[(2-O-D-Apio-b-D-furanosyl-b-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Apigenin-7-apiosylglucoside EINECS 247-780-0

Description	Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Mencherini T, et al. An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties. J Pharm Pharmacol. 2007 Jun;59(6):891-7.

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RIDADR	NONH for all modes of transport
WGK Germany	1
HS Code	29389090

Precursor 0
DownStream 3
2280-44-6 520-36-5 578-74-5