Apiin

Modify Date: 2024-01-02 17:13:42

Apiin Structure
Apiin structure
Common Name Apiin
CAS Number 26544-34-3 Molecular Weight 564.492
Density 1.7±0.1 g/cm3 Boiling Point 942.2±65.0 °C at 760 mmHg
Molecular Formula C26H28O14 Melting Point 230ºC (dec.)
MSDS Chinese USA Flash Point 316.7±27.8 °C

 Use of Apiin


Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells[1].

 Names

Name Apiin
Synonym More Synonyms

 Apiin Biological Activity

Description Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells[1].
Related Catalog
References

[1]. Mencherini T, et al. An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties. J Pharm Pharmacol. 2007 Jun;59(6):891-7.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 942.2±65.0 °C at 760 mmHg
Melting Point 230ºC (dec.)
Molecular Formula C26H28O14
Molecular Weight 564.492
Flash Point 316.7±27.8 °C
Exact Mass 564.147888
PSA 228.97000
LogP 0.74
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.744
Storage condition 2-8C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 1
HS Code 29389090

 Precursor & DownStream

Precursor  0

DownStream  3

 Articles7

More Articles
Evaluation of detection sensitivity in comprehensive two-dimensional liquid chromatography separations of an active pharmaceutical ingredient and its degradants.

Anal. Bioanal. Chem 407(1) , 265-77, (2015)

In this paper, we describe the findings of a study aimed at assessing the detection sensitivity of comprehensive two-dimensional high-performance liquid chromatography (LCxLC) separation of a degraded...

Bioavailability of apigenin from apiin-rich parsley in humans.

Ann. Nutr. Metab. 50(3) , 167-72, (2006)

Absorption and excretion of apigenin after the ingestion of apiin-rich food, i.e. parsley, was tested.Eleven healthy subjects (5 women, 6 men) in the age range of 23-41 years and with an average body ...

[Studies on the chemical constituents of the aerial parts of Seseli mairei].

Zhong Yao Cai 30(1) , 42-4, (2007)

To study the chemical constituents of the aerial parts of Seseli mairei Wolf.The chemical constituents have been separated with manifold chromatography methods, and their structures were determined hy...

 Synonyms

APIIN
Apioside
APIGENIN-7-APIOGLUCOSIDE
5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 4-O-[(3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl]-β-D-glucopyranoside
apigenin-7-O-apiosyl(1->2)glucoside
apigenin 7-O-apiosylglucoside
4',5,7-Trihydroxyflavone-7-apiosylglucoside
4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-[[4-O-[(3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-β-D-glucopyranosyl]oxy]-
5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 4-O-[(3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-β-D-glucopyranoside
7-(2-APIOSYLGLUCOSYL)APIGENIN
Apigenin-7-(2-O-apiosylglucoside)
7-[(2-O-D-Apio-b-D-furanosyl-b-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Apigenin-7-apiosylglucoside
EINECS 247-780-0
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