113-79-1

113-79-1 structure

Name: Argipressin
Chemical Name: Arginine Vasopressin
CAS Number: 113-79-1
Molecular Formula: C₄₆H₆₅N₁₅O₁₂S₂
Molecular Weight: 1084.232
Catalog: API Urinary system medication Diabetes insipidus medication
Create Date: 2018-02-05 08:00:00
Modify Date: 2024-01-02 20:17:58
Argipressin binds to the V1-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells. Sequence: CysTyrPheGlnAsnCysProArgGly-NH2(Disulfide bridge: Cys1-Cys6).

Name	Arginine Vasopressin
Synonyms	EINECS 204-035-4 MFCD00133939 Argipressine [Arg8]-Vasopressin (AVP) CYS-TYR-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2 Argipressin Acetate Argipressin

Description	Argipressin binds to the V1-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells. Sequence: CysTyrPheGlnAsnCysProArgGly-NH2(Disulfide bridge: Cys1-Cys6).
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Peptides
In Vitro	Argipressin binds to the vascular arginine vasopressin receptor, V1, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells. It also stimulates the intracellular release of calcium in A7r5 cells (EC50=5 nM)[1]. AVP-induced [Ca2+]i signals and immunized activity against S-100 in DRG cell culture. The minimum effective concentrations of Argipressin causing [Ca2+]i responses are 100 pM in non-neuronal cells in DRG culture[2].
References	[1]. Thibonnier M, et al. Multiple signaling pathways of V1-vascular vasopressin receptors of A7r5 cells. Endocrinology. 1991 Dec;129(6):2845-56. [2]. Moriya T, et al. Vasopressin-induced intracellular Ca²⁺ concentration responses in non-neuronal cells of the rat dorsal root ganglion. Brain Res. 2012 Nov 5;1483:1-12.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H332
Precautionary Statements	P261
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R20
Safety Phrases	36
RIDADR	NONH for all modes of transport
WGK Germany	3