Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Azido-PEG8-amine
Price: ￥2378.0/500mg
Purity: 95.0%
Stocking Period: Inquiry
Contact: Liu jia

Chengdu Pukang Biotechnology Co., Ltd.
China
Product Name: 3,6,9,12,15,18,21,24-Octaoxahexacosan-1-amine,26-azido-
Price: ￥Inquiry/10g
Purity: 95.0%
Stocking Period: Inquiry
Contact: Lihua Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)HEPTAETHYLENE GLYCOL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

857891-82-8

857891-82-8 structure

857891-82-8 structure

Name: Azido-PEG8-amine
Chemical Name: 2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
CAS Number: 857891-82-8
Molecular Formula: C₁₈H₃₈N₄O₈
Molecular Weight: 438.51600
Catalog: Chemical reagent Organic reagent Azide
Create Date: 2017-03-04 16:00:23
Modify Date: 2024-01-04 18:24:03
Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonyms	Azido-PEG-amine (n=8) O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol O-(2-Aminoethyl)-O inverted exclamation marka-(2-azidoethyl)heptaethylene glycol 26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine

Description	Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₈H₃₈N₄O₈
Molecular Weight	438.51600
Exact Mass	438.26900
PSA	149.61000
LogP	0.54126
Storage condition	2-8°C

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26
RIDADR	NONH for all modes of transport
WGK Germany	3