Azido-PEG8-amine structure
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Common Name | Azido-PEG8-amine | ||
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CAS Number | 857891-82-8 | Molecular Weight | 438.51600 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C18H38N4O8 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Azido-PEG8-amineAzido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | 2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
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Synonym | More Synonyms |
Description | Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C18H38N4O8 |
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Molecular Weight | 438.51600 |
Exact Mass | 438.26900 |
PSA | 149.61000 |
LogP | 0.54126 |
Storage condition | 2-8°C |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xi: Irritant; |
Risk Phrases | 36/37/38 |
Safety Phrases | 26 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Spatioselective Modification of Bicompartmental Polymer Particles and Fibers via Huisgen 1, 3‐Dipolar Cycloaddition Bhaskar S, et al.
Macromol. Rapid Commun. 29(20) , 1655-1660, (2008)
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Azido-PEG-amine (n=8) |
O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol |
O-(2-Aminoethyl)-O inverted exclamation marka-(2-azidoethyl)heptaethylene glycol |
26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine |